Literature DB >> 701088

Hb Nottingham (alpha2beta2 (FG5) 98 val leads to gly) in a Caucasian male: clinical and biosynthetic studies.

E P Orringer, A Felice, A Reese, J B Wilson, H Lam, M E Gravely, T H Huisman.   

Abstract

A second instance of the unstable mutant Hb Nottingham (alpha2beta2 (FG5) 98 Val leads to Gly) is reported in a 7-year-old boy. Because of splenomegaly, cholelithiasis, and frequent episodes of abdominal pain, he underwent a splenectomy and cholecystectomy at age 6. The surgery resulted in both an amelioration of his RBC destruction and an acceleration of his rate of growth.

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Year:  1978        PMID: 701088     DOI: 10.3109/03630267809005343

Source DB:  PubMed          Journal:  Hemoglobin        ISSN: 0363-0269            Impact factor:   0.849


  1 in total

1.  Hb Nottingham or alpha 2 beta 2 98 (FG5) Val-->Gly in a Czech child.

Authors:  V Brabec; K Indrák; H Fortová; J Suttnar; B Blazek; J Cermák; V Divoký; L Vepreková; J Zeman
Journal:  Ann Hematol       Date:  1994-08       Impact factor: 3.673

  1 in total

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