Literature DB >> 7009011

Ectopic bone formation and aging.

J T Irving, S A LeBolt, E L Schneider.   

Abstract

Six-week-old, 6-month-old, and 2-year-old female rats of the Wistar strain were implanted with decalcified bone powder prepared from rats of the same strain. An encapsulated deposit of cartilage and bone formed. The deposits were removed at intervals and studied histologically and after administration of 45Ca. Intramembranous bone formed in 14 days in the 6-week-old animals, but was not seen until the 23rd day in the 2-year-old rats. This implant system may provide a model for the study of the mechanisms for the decline of osteogenesis, or the low bone formation rate which occurs with aging.

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Year:  1981        PMID： 7009011

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN： 0009-921X            Impact factor:   4.176


  10 in total

1.  Aging effect on inductive capacity of human demineralized bone matrix.

Authors:  C Nyssen-Behets; O Delaere; P Y Duchesne; A Dhem
Journal:  Arch Orthop Trauma Surg       Date:  1996       Impact factor: 3.067

2.  The effect of aging on bone formation in rats: biochemical and histological evidence for decreased bone formation capacity.

Authors:  S K Nishimoto; C H Chang; E Gendler; W F Stryker; M E Nimni
Journal:  Calcif Tissue Int       Date:  1985-12       Impact factor: 4.333

3.  The effect of deficiencies of manganese and copper on osteoinduction and on resorption of bone particles in rats.

Authors:  L Strause; P Saltman; J Glowacki
Journal:  Calcif Tissue Int       Date:  1987-09       Impact factor: 4.333

4.  The effect of aging on fracture healing in the rat.

Authors:  B Bak; T T Andreassen
Journal:  Calcif Tissue Int       Date:  1989-11       Impact factor: 4.333

5.  Effects of acetylsalicylic acid on heterotopic bone resorption and formation in rats.

Authors:  L F Solheim; H Rönningen; N Langeland
Journal:  Arch Orthop Trauma Surg       Date:  1986

6.  Effect of bone marrow cell collection techniques and donor site locations on in-vitro growth of bone forming cells.

Authors:  Sung Min Chung; Eun-Bok Kim; So-Young Park; Min Chul Sung; Hyun Kook Youn; Myun-Whan Ahn
Journal:  Asian Spine J       Date:  2008-12-31

Review 7.  Bone morphogenetic protein: a review.

Authors:  G Aldinger; G Herr; W Küsswetter; H J Reis; F W Thielemann; U Holz
Journal:  Int Orthop       Date:  1991       Impact factor: 3.075

8.  Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage.

Authors:  Lakshman Singh; Tracy A Brennan; Elizabeth Russell; Jung-Hoon Kim; Qijun Chen; F Brad Johnson; Robert J Pignolo
Journal:  Bone       Date:  2016-01-19       Impact factor: 4.398

9.  Bone progenitor cell deficits and the age-associated decline in bone repair capacity.

Authors:  R Quarto; D Thomas; C T Liang
Journal:  Calcif Tissue Int       Date:  1995-02       Impact factor: 4.333

10.  Expression of insulin-like growth factors during bone induction in rat.

Authors:  P T Prisell; D Edwall; J B Lindblad; A Levinovitz; G Norstedt
Journal:  Calcif Tissue Int       Date:  1993-09       Impact factor: 4.333
  10 in total

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