Literature DB >> 7007666

Prophylactic antibiotics in simple hand lacerations.

J A Grossman, J P Adams, J Kunec.   

Abstract

A randomized prospective study of 265 patients with hand lacerations was carried out to define the role of prophylactic antibiotics in the management of simple, sutured wounds of the hand. Two hundred sixty-five patients were followed up until suture removal or satisfactory wound healing. There were a total of three infections (1.1%). There was no noticeable differences in the incidence of infection in the antibiotic and placebo treatment groups. It is concluded that prophylactic antibiotics are an unnecessary adjunct in the treatment of simple lacerations of the hand and no replacement for meticulous wound management.

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Year:  1981        PMID: 7007666

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  9 in total

Review 1.  Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Prophylactic antibiotics are not indicated in uncomplicated hand lacerations.

Authors:  Shafic S Al-Nammari; Adam J Reid
Journal:  Emerg Med J       Date:  2007-03       Impact factor: 2.740

2.  Antibiotic Use in Hand Surgery: Surgeon Decision Making and Adherence to Available Evidence.

Authors:  John C Dunn; Kenneth R Means; Sameer Desale; Aviram M Giladi
Journal:  Hand (N Y)       Date:  2018-11-22

3.  The risk of wound infection after simple hand laceration.

Authors:  Gholamreza S Roodsari; Farhad Zahedi; Shahriar Zehtabchi
Journal:  World J Emerg Med       Date:  2015

4.  Surgical Antimicrobial Prophylaxis in Pediatric Patients Undergoing Plastic Surgery: A RAND/UCLA Appropriateness Method Consensus Study.

Authors:  Susanna Esposito; Rossella Sgarzani; Sonia Bianchini; Sara Monaco; Laura Nicoletti; Erika Rigotti; Marilia Di Pietro; Roberta Opri; Caterina Caminiti; Matilde Ciccia; Giorgio Conti; Daniele Donà; Mario Giuffré; Stefania La Grutta; Laura Lancella; Mario Lima; Andrea Lo Vecchio; Gloria Pelizzo; Giorgio Piacentini; Carlo Pietrasanta; Matteo Puntoni; Alessandro Simonini; Elisabetta Venturini; Annamaria Staiano; Nicola Principi
Journal:  Antibiotics (Basel)       Date:  2022-04-11

5.  Traumatic lacerations: what are the risks for infection and has the 'golden period' of laceration care disappeared?

Authors:  James V Quinn; Steven K Polevoi; Michael A Kohn
Journal:  Emerg Med J       Date:  2013-01-12       Impact factor: 2.740

6.  Prophylactic Antibiotic Therapy in Contaminated Traumatic Wounds: Two Days versus Five Days Treatment.

Authors:  Hamed-Basir Ghafouri; Barzin Bagheri-Behzad; Mohammad-Reza Yasinzadeh; Ehsan Modirian; Dorsa Divsalar; Shervin Farahmand
Journal:  Bioimpacts       Date:  2012-03-17

Review 7.  Immune response to traumatic injury: harmony and discordance of immune system homeostasis.

Authors:  Akinori Osuka; Hiroshi Ogura; Masashi Ueyama; Takeshi Shimazu; James A Lederer
Journal:  Acute Med Surg       Date:  2014-01-28

8.  Antibiotic prescribing practices of emergency physicians and patient expectations for uncomplicated lacerations.

Authors:  Samuel Ong; Gregory J Moran; Anusha Krishnadasan; David A Talan
Journal:  West J Emerg Med       Date:  2011-11

Review 9.  The Use of Preoperative Antibiotics in Elective Soft-Tissue Procedures in the Hand: A Critical Analysis Review.

Authors:  Lauren M Shapiro; Thompson Zhuang; Kevin Li; Robin N Kamal
Journal:  JBJS Rev       Date:  2019-08
  9 in total

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