Literature DB >> 70076

Autoantibodies to zona pellucida: a possible cause for infertility in women.

C A Shivers, B S Dunbar.   

Abstract

Human and pig ovaries were tested by agar gel diffusion and found to contain several cross-reacting (common) antigens. At least one common antigen was located in the zona pellucida as determined by indirect immunofluorescence. Serum samples from 22 infertile women were tested on pig eggs by immunofluorescence, and six of these samples produced strong and nine produced moderate reactions with the zona pellucida. The autoantibodies may be responsible for infertility in these women.

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Year:  1977        PMID： 70076     DOI： 10.1126/science.70076

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

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2.  Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure.

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Review 3.  Multiplicity of molecular and cellular targets in human ovarian autoimmunity: an update.

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Review 4.  Immunology of the sperm-egg interaction.

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5.  A new method for detection of anti-zona activity in human sera using latex agglutination reaction.

Authors:  Y Noda; I Yamada; S Hayashi; I Takai; E Watanabe
Journal:  Experientia       Date:  1983-08-15

6.  Immunofluorescence studies on autoantibodies to steroid-producing cells, and to germline cells in endocrine disease and infertility.

Authors:  F Sotsiou; G F Bottazzo; D Doniach
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7.  Antibodies to two ZP3 B cell epitopes affect zona pellucida assembly.

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8.  Deposition of immune complexes in ovarian follicles of mice with lupus-like syndrome.

Authors:  L Accinni; B Albini; G Andres; F J Dixon
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Review 9.  Infertility and Immunocontraception based on zona pellucida.

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10.  Autoimmune oophoritis in thymectomized mice: detection of circulating antibodies against oocytes.

Authors:  O Taguchi; Y Nishizuka; T Sakakura; A Kojima
Journal:  Clin Exp Immunol       Date:  1980-06       Impact factor: 4.330
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