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Literature DB >> 7007295

Alpha-endorphin-like immunoreactivity in plasma cells of the canine colonic mucosa.

Abstract

During immunocytochemical investigations on the presence of opioid peptides in gastrointestinal endocrine cells it was found that a subpopulation of plasma cells located in the lamina propria of the canine colonic mucosa showed immunoreactivities for alpha-endorphin. All immunohistochemical specificity controls proved the specificity of the reaction. Circumstantial evidence suggest, however, that no authentic alpha-endorphin is present within this cell type. Possibly sequence homologies between alpha-endorphin and the amino acid composition of a certain immunoglobulin are responsible for the immunocytochemically specific alpha-endorphin-like immunoreactivity of plasma cells.

Entities: Disease Species

Mesh：

Substances：
Endorphins

Year: 1980 PMID： 7007295 DOI： 10.1007/bf00533132

Source DB: PubMed Journal: Histochemistry ISSN： 0301-5564

16 in total

3. A new hypothalamic substance, and not luteinizing hormone-releasing hormone, is detected immunocytochemically by antibody to luteinizing hormone-releasing hormone.

Authors: L A Sternberger; J L Greenwald; D Hock; K Elger; W G Forssmann
Journal: Proc Natl Acad Sci U S A Date: 1981-08 Impact factor: 11.205

3 in total

Alpha-endorphin-like immunoreactivity in plasma cells of the canine colonic mucosa.

1. Embedding in epoxy resins for ultrathin sectioning in electron microscopy.

2. Endorphins: new gut peptides with a familiar face.

3. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.

4. Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands.

5. Isolation of peptides with opiate activity from sheep and human pituitaries: relationship to beta-lipotropin.

6. Analysis of the common precursor to corticotropin and endorphin.

7. High-molecular-weight immunoreactive beta-endorphin in extracts of human placenta is a fragment of immunoglobulin G.

8. Pancreatic glucagon cells contain endorphin-like immunoreactivity.

9. Immunoreactivities of gastrin (G-) cells. I. dilution-dependent staining of G-cells by antisera and non-immune sera.

10. A simple method for removing the resin from epoxy-embedded tissue.

1. [The endocrine cells of the digestive system (author's transl)].

2. Evidence for an inhibitory role of beta-endorphin and other opioids on human total T rosette formation.

3. A new hypothalamic substance, and not luteinizing hormone-releasing hormone, is detected immunocytochemically by antibody to luteinizing hormone-releasing hormone.