Literature DB >> 7006874

Spontaneous antibody-secreting human blood lymphocytes detected with a protein A plaque assay.

T Kunori, P Broman, M Tan.   

Abstract

Spontaneous antibody-secreting lymphocytes in human peripheral blood were detected and counted by a protein A plaque assay. The level of plaque-forming cells (PFC) in peripheral blood was significantly higher in patients with immune disorders (per 10(6) lymphocytes: IgG PFC, 2,654 +/- 684; IgA PFC, 1,727 +/- 327; IgM PFC, 403 +/- 92) than in normal controls (per 10(6) lymphocytes: IgG PFC, 327 +/- 56; IgA PFC 633 +/- 128; IgM PFC, 215 +/- 105). There was no direct correlation between the PFC numbers of different Ig classes.

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Year:  1980        PMID： 7006874      PMCID： PMC1537057     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  8 in total

1.  The use of bacteria for the functional characterization of human lymphocyte subpopulations in various lymphoid organs.

Authors:  B Rynnel-Dagöö; O Ringdén; H Alfredsson; E Möller
Journal:  Scand J Immunol       Date:  1978       Impact factor: 3.487

Review 2.  Induction of antibody synthesis in human B lymphocytes by different polyclonal B cell activators: evaluation by direct and indirect PFC assays.

Authors:  O Ringdén; B Rynnel-Dagöö; T Kunori; C I Smith; L Hammarström; A Freijd; E Möller
Journal:  Immunol Rev       Date:  1979       Impact factor: 12.988

Review 3.  The atypical lymphocyte.

Authors:  T A Wood; E P Frenkel
Journal:  Am J Med       Date:  1967-06       Impact factor: 4.965

4.  A plaque assay for all cells secreting Ig of a given type or class.

Authors:  E Gronowicz; A Coutinho; F Melchers
Journal:  Eur J Immunol       Date:  1976-08       Impact factor: 5.532

5.  Optimal conditions for polyclonal antibody secretion and DNA synthesis in human blood and spleen lymphocytes by lipopolysaccharide.

Authors:  T Kunori; O Ringdén; E Möller
Journal:  Scand J Immunol       Date:  1978       Impact factor: 3.487

6.  Polyclonal antibody secretion in human lymphocytes induced by killed staphylococcal bacteria and by lipopolysaccharide.

Authors:  O Ringdén; B Rynnel-Dagöö; E M Waterfield; E Möller; G Möller
Journal:  Scand J Immunol       Date:  1977       Impact factor: 3.487

7.  Activation of human B lymphocytes. I. Direct plaque-forming cell assay for the measurement of polyclonal activation and antigenic stimulation of human B lymphocytes.

Authors:  A S Fauci; K R Pratt
Journal:  J Exp Med       Date:  1976-09-01       Impact factor: 14.307

8.  Lymphoid cellular responses in the blood after immunization in man.

Authors:  D Crowther; G H Fairley; R L Sewell
Journal:  J Exp Med       Date:  1969-05-01       Impact factor: 14.307
  8 in total
  5 in total

1.  In vitro effects of human lipoproteins on the immune system in healthy donors: inhibition of plaque forming cell generation and decreased frequency of NK cells.

Authors:  S Antonaci; E Jirillo; M T Ventura; A Capurso; A R Garofalo; L Bonomo
Journal:  Clin Exp Immunol       Date:  1984-06       Impact factor: 4.330

2.  Clinical evaluation of B cell and T-regulator cell function using a protein A haemolytic plaque assay.

Authors:  B M Jones
Journal:  Clin Exp Immunol       Date:  1981-10       Impact factor: 4.330

3.  Pseudoplaque formation by cytophilic immunoglobulins in the sera of lupus patients as measured using reverse haemolytic plaque assay.

Authors:  M Okubo; K Kamata; T Uchiyama
Journal:  Clin Exp Immunol       Date:  1982-05       Impact factor: 4.330

4.  Distribution of IgM, IgA and IgG secreting cells in the tissues of normal and tumour-bearing mice.

Authors:  S Howie; W H McBride; K James
Journal:  Immunology       Date:  1982-05       Impact factor: 7.397

5.  Spontaneous antibody-secreting cells in the stomach of gastric cancer patients.

Authors:  T Kunori; F Shinya; T Satomi; J Itoh; M Abe; M Takahashi; T Yokota; Y Abe; K Hiraoka; S Kawaguchi; I Tanaka; M Mochizuki; S Asano
Journal:  J Gastroenterol       Date:  1996-04       Impact factor: 7.527
  5 in total

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