Isolated mitral valve replacement and ventricular rupture: presentation of 6 patients.

The cases of 6 patients who had ventricular wall rupture after isolated mitral valve replacement and were seen in our service are reviewed. In the first 2, the main lesion was mitral stenosis and calcification was severe. Injury to the ventricular myocardium during removal of the valve was the causative factor in 1 and the most likely explanation in the other. In the other 4 patients, the dominant lesion was insufficiency. Calcium was absent, and fibrosis of the valves was minimal. Defects of technique were not obvious. All perforations were beneath the annulus. The first of these 4 latter patients underwent operation just after cardioplegic solutions were introduced for myocardial protection in our service. During that period, the incidence of ventricular wall rupture was 7.3% for mitral valve replacement (55 patients). Causing 3 deaths, it became the most important mortality factor. After reviewing the problem, we decided to change our technique by leaving practically all the posterior leaflet and most of the chords intact and placing sutures through fibrous tissue only, never into muscle, as had already been suggested. Since then, we have not seen another rupture in 23 valve replacements.