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Literature DB >> 7004346

Quantitative correlation between penicillin resistance and beta-lactamase activity specified by the R plasmids R1, R1 bla-45, and RP1 in Escherichia coli K-12.

Abstract

A mutant of the R plasmid R1 which synthesizes a beta-lactamase with altered kinetic characteristics was isolated. The level of penicillin resistance specified by this plasmid was correctly predicted from the properties of the wild-type R1 according to a simple theoretical model published by Zimmermann and Rosselet (Antimicrob. Agents Chemother. 12:368--372, 1977). The model also accounts for the high level of penicillin resistance specified by the R plasmid RP1.

Entities: Chemical Species

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Year: 1980 PMID： 7004346 PMCID： PMC284074 DOI： 10.1128/AAC.18.5.675

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

21 in total

Review 1. The beta-lactamases of gram-negative bacteria and their possible physiological role.

Authors: M H Richmond; R B Sykes
Journal: Adv Microb Physiol Date: 1973 Impact factor: 3.517

2. Variant of penicillinase mediated by an R factor in Escherichia coli.

Authors: T Sawai; K Takahashi; S Yamagishi; S Mitsuhashi
Journal: J Bacteriol Date: 1970-11 Impact factor: 3.490

3. Inhibition of beta-lactamases by beta-lactam antibiotics.

Authors: C O'Callaghan; A Morris
Journal: Antimicrob Agents Chemother Date: 1972-12 Impact factor: 5.191

4. The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12.

Authors: E Meynell; N Datta
Journal: Genet Res Date: 1966-02 Impact factor: 1.588

5. Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12.

Authors: B G Spratt
Journal: Proc Natl Acad Sci U S A Date: 1975-08 Impact factor: 11.205

6. A direct spectrophotometric assay and determination of Michaelis constants for the beta-lactamase reaction.

Authors: A Samuni
Journal: Anal Biochem Date: 1975-01 Impact factor: 3.365

7. The purification and properties of a penicillinase whose synthesis is mediated by an R-factor in Escherichia coli.

Authors: N Datta; M H Richmond
Journal: Biochem J Date: 1966-01 Impact factor: 3.857

8. Release of surface enzymes in Enterobacteriaceae by osmotic shock.

Authors: H C Neu; J Chou
Journal: J Bacteriol Date: 1967-12 Impact factor: 3.490

9. Effect of R-factor-mediated genes on some surface properties of Escherichia coli.

Authors: N A Curtis; M H Richmond
Journal: Antimicrob Agents Chemother Date: 1974-12 Impact factor: 5.191

10. Properties of a R factor which originated in Pseudomonas aeruginosa 1822.

Authors: J Grinsted; J R Saunders; L C Ingram; R B Sykes; M H Richmond
Journal: J Bacteriol Date: 1972-05 Impact factor: 3.490

5 in total

1. Social behaviour involving drug resistance: the role of initial density, initial frequency and population structure in shaping the effect of antibiotic resistance as a public good.

Authors: I L Domingues; J A Gama; L M Carvalho; F Dionisio
Journal: Heredity (Edinb) Date: 2017-06-21 Impact factor: 3.821

5. Characterization of beta-lactamase-deficient (bla) mutants of the R plasmid R1 in Escherichia coli K-12 and comparison with similar mutants of RP1.

Authors: I Crowlesmith; T G Howe
Journal: Antimicrob Agents Chemother Date: 1980-11 Impact factor: 5.191