Literature DB >> 7003573

Papaverine and hepatotoxicity.

M S Pathy, A J Reynolds.   

Abstract

Six of 14 patients receiving a sustained release papaverine preparation developed abnormal liver function tests. One patient had jaundice and another abnormal liver histology on a biopsy specimen. This is only the third report of impaired liver function following the administration of papaverine--a drug which has been used in clinical medicine for over 100 years.

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Year:  1980        PMID: 7003573      PMCID: PMC2425822          DOI: 10.1136/pgmj.56.657.488

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  7 in total

Review 1.  VASORELAXANT DRUGS AND CEREBROVASCULAR DISEASE.

Authors:  J R WHITTIER
Journal:  Angiology       Date:  1964-02       Impact factor: 3.619

2.  The effect of intravenous papaverine hydrochloride on the cerebral circulation.

Authors:  H W JAYNE; P SCHEINBERG; M RICH; M S BELLE
Journal:  J Clin Invest       Date:  1952-01       Impact factor: 14.808

3.  Papaverine--safety in use.

Authors:  M R Gilliss
Journal:  J Am Geriatr Soc       Date:  1973-05       Impact factor: 5.562

4.  Management of chronic brain syndrome secondary to cerebral arteriosclerosis, with special reference to papaverine hydrochloride.

Authors:  F H Stern
Journal:  J Am Geriatr Soc       Date:  1970-06       Impact factor: 5.562

5.  Papaverine--hepatotoxic or not?

Authors:  P M Driemen
Journal:  J Am Geriatr Soc       Date:  1973-05       Impact factor: 5.562

6.  Papaverine revisited as a hepatotoxin.

Authors:  H J Zimmerman
Journal:  N Engl J Med       Date:  1969-12-11       Impact factor: 91.245

7.  Hepatotoxicity due to treatment with papaverine. Report of four cases.

Authors:  V Ronnov-Jessen; A Tjernlund
Journal:  N Engl J Med       Date:  1969-12-11       Impact factor: 91.245

  7 in total
  2 in total

Review 1.  Drug effects on the liver. An updated tabular compilation of drugs and drug-related hepatic diseases.

Authors:  J Ludwig; R Axelsen
Journal:  Dig Dis Sci       Date:  1983-07       Impact factor: 3.199

2.  Synthesis and fluorescent properties of boroisoquinolines, a new family of fluorophores.

Authors:  Dénes Sóvári; Attila Kormos; Orsolya Demeter; András Dancsó; György Miklós Keserű; Mátyás Milen; Péter Ábrányi-Balogh
Journal:  RSC Adv       Date:  2018-11-15       Impact factor: 3.361

  2 in total

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