Literature DB >> 7003166

Study of Plasmodium falciparum resistance to 4-Aminoquinolines (Chloroquine) in Sabah, Malaysia.

K M Maqsudur Rahman.   

Abstract

The status of P. falciparum resistance to chloroquine in Sabah, Malaysia were not know until 1971-1972. Several in-vivo and on in-vivo studies were conducted from 971-1975, and the result showed 51% out of total 57 cases studied were resistant to chloroquine. The latest in-vitro study (collaborative with WHO) started in July 1978, to continue till 1980, to cover the whole State. The preliminary result shows 65 cases (85%) out of a total 76 successful tests are resistant to chloroquine. On the basis of this preliminary result, the radical treatment for P. falciparum infection was changed from chloroquine to Fansidar from June 1979 throughout the State.

Entities:  

Keywords:  Asia; Communicable Disease Control; Delivery Of Health Care; Developing Countries; Diseases; Health; Health Services; In Vitro; Malaysia; Parasite Control; Parasitic Diseases; Public Health; Southeastern Asia; Who

Mesh:

Substances:

Year:  1980        PMID: 7003166

Source DB:  PubMed          Journal:  J Trop Med Hyg        ISSN: 0022-5304


  2 in total

1.  Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.

Authors:  Timothy William; Jayaram Menon; Giri Rajahram; Leslie Chan; Gordon Ma; Samantha Donaldson; Serena Khoo; Charlie Frederick; Jenarun Jelip; Nicholas M Anstey; Tsin Wen Yeo
Journal:  Emerg Infect Dis       Date:  2011-07       Impact factor: 6.883

2.  Full-length sequence analysis of chloroquine resistance transporter gene in Plasmodium falciparum isolates from Sabah, Malaysia.

Authors:  Lii Lian Tan; Tiek Ying Lau; William Timothy; Dhanaraj Prabakaran
Journal:  ScientificWorldJournal       Date:  2014-10-28
  2 in total

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