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Literature DB >> 7002765

Hidden Thy-1 antigen in a subpopulation of mouse bone marrow cells.

M A Ritter, R J Morris, I Goldschneider.

Abstract

Immunofluorescence and cytolysis studies using antisera against the xeno- and alloantigenic components of the Thy-1 molecule have shown that in adult mouse bone marrow more cells bear the xeno than the alloantigen. Allo+ cells form a subset of a larger, xeno+ population. Xeno+ allo- 'prothymocytes' can be induced to express the alloantigen in vitro; this could result from the unmasking of cryptic antigen, the presence of which is demonstrated, rather than de novo antigen synthesis. Some xeno+ allo- cells are involved in splenic haemopoiesis, either as a subpopulation of precursors, or as accessory helper cells.

Entities: Disease Gene Species

Mesh：

Substances：
Isoantigens

Year: 1980 PMID： 7002765 PMCID： PMC1457790

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

35 in total

1. Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation.

Authors: B Storrie; G Goldstein; E A Boyse; U Hammerling
Journal: J Immunol Date: 1976-05 Impact factor: 5.422

2. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.

Authors: J E TILL; E A McCULLOCH
Journal: Radiat Res Date: 1961-02 Impact factor: 2.841

3. Studies on thymus products. VI. The effects of cyclic nucleotides and prostaglandins on rosette-forming cells. Interactions with thymic factor.

Authors: M A Bach; J F Bach
Journal: Eur J Immunol Date: 1973-12 Impact factor: 5.532

4. The separation of different cell classes from lymphoid organs. II. The purification and analysis of lymphocyte populations by equilibrium density gradient centrifugation.

Authors: K Shortman
Journal: Aust J Exp Biol Med Sci Date: 1968-08

5. Absorption of guinea pig serum with agar. A method for elimination of itscytotoxicity for murine thymus cells.

Authors: A Cohen; M Schlesinger
Journal: Transplantation Date: 1970-07 Impact factor: 4.939

6. Serological and preliminary biochemical characteristics of a T lymphocyte differentiation antigen detected by rabbit antiserum to rat thymocyte membranes.

Authors: R J Morris; A F Williams
Journal: Eur J Immunol Date: 1977-06 Impact factor: 5.532

7. Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. I. Isolation of pluripotent hemopoietic stem cells and granulocyte-macrophage progenitor cells.

Authors: I Goldschneider; D Metcalf; F Battye; T Mandel
Journal: J Exp Med Date: 1980-08-01 Impact factor: 14.307

7 in total

Hidden Thy-1 antigen in a subpopulation of mouse bone marrow cells.

1. Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation.

2. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.

3. Studies on thymus products. VI. The effects of cyclic nucleotides and prostaglandins on rosette-forming cells. Interactions with thymic factor.

4. The separation of different cell classes from lymphoid organs. II. The purification and analysis of lymphocyte populations by equilibrium density gradient centrifugation.

5. Absorption of guinea pig serum with agar. A method for elimination of itscytotoxicity for murine thymus cells.

6. Serological and preliminary biochemical characteristics of a T lymphocyte differentiation antigen detected by rabbit antiserum to rat thymocyte membranes.

7. Immature T lineage lymphocytes in athymic mice. Presence of TL, lifespan and homeostatic regulation.

8. Synapse formation between clonal neuroblastoma X glioma hybrid cells and striated muscle cells.

9. Demonstration of Thy-1 antigen on pluripotent hemopoietic stem cells in the rat.

10. Brain-associated stem cell antigen: an antigen shared by brain and hemopoietic stem cells.

1. Cyclosporin A prevents the in vivo development of murine prothymocytes from uncommitted (Thy-1-) precursor cells.

2. Sequential activation and loss of the pre-B cell Thy-1 gene in T-cell X pre-B cell somatic hybrids.

3. Expression of Thy-1 antigen is not limited to T cells in cultures of mouse hemopoietic cells.

4. Differential regulation of a Thy-1 gene in transgenic mice.

5. Association of thy-1 cell surface differentiation antigen with certain connective tissues in vivo.

6. Determination of the molecular nature and cellular localization of Thy-1 in human renal tissue.

7. Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. I. Isolation of pluripotent hemopoietic stem cells and granulocyte-macrophage progenitor cells.