Literature DB >> 7002584

A selective concentration-dependent dysrhythmogenic and antidysrhythmic action of prostaglandins E2, F2 alpha and I2 (prostacyclin) on isolated rat hearts.

M Karmazyn, N S Dhalla.   

Abstract

Prostaglandins (PGs) E2, F2 alpha and I2 were examined for their effects on the electrical and mechanical activities of isolated rat, rabbit and guinea-pig hearts. All PGs produced dysrhythmias in rat hearts at low concentrations only, while higher concentrations were antiarrhythmic. Guinea-pig hearts were less responsive while rabbit hearts were completely resistant.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 7002584     DOI： 10.1007/bf01953843

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Effects of prostaglandins on experimental arrhythmias.

Authors:  H J Mest; P Mentz; W Förster
Journal:  Pol J Pharmacol Pharm       Date:  1974 Jan-Apr

2.  Prostaglandin E 1 and cardiac arrhythmia.

Authors:  W G Zijlstra; J R Brunsting; F ten Hoor; A J Vergroesen
Journal:  Eur J Pharmacol       Date:  1972-05       Impact factor: 4.432

3.  Prostaglandins and prostaglandin precursors as endogenous antiarrhythmic principles of the heart.

Authors:  W Förster
Journal:  Acta Biol Med Ger       Date:  1976

4.  Action of prostaglandins on heart arrhythmias.

Authors:  D Mann
Journal:  Acta Biol Med Ger       Date:  1976

5.  Anoxia-induced release of prostaglandins in rabbit isolated hearts.

Authors:  A J Block; H Feinberg; K Herbaczynska-Cedro; J R Vane
Journal:  Circ Res       Date:  1975-01       Impact factor: 17.367

6.  Roles of prostaglandins suggested by the prostaglandin agonist/antagonist actions of local anaesthetic, anti-arrhythmic, anti-malarial, tricyclic anti-depressant and methyl xanthine compounds. Effects on membranes and on nucleic acid function.

Authors:  D F Horrobin; M S Manku
Journal:  Med Hypotheses       Date:  1977 Mar-Apr       Impact factor: 1.538

7.  Low prostaglandin concentrations cause cardiac rhythm disturbances. Effect reversed by low levels of copper or chloroquine.

Authors:  A Swift; M Karmazyn; D F Horrobin; M S Manku; R A Karmali; R O Morgan; A I Ally
Journal:  Prostaglandins       Date:  1978-04

8.  The influence of prostacyclin on coronary occlusion induced arrhythmia in cats.

Authors:  R K Dix; G J Kelliher; N Jurkiewicz; T Lawrence
Journal:  Prostaglandins Med       Date:  1979-09

9.  Antiarrhythmic effects of aspirin during nonthrombotic coronary occlusion.

Authors:  C B Moschos; B Haider; C De La Cruz; M M Lyons; T J Regan
Journal:  Circulation       Date:  1978-04       Impact factor: 29.690

10.  Early prostaglandin release from the ischemic myocardium in the dog.

Authors:  M L Ogletree; J T Flynn; M Feola; A M Lefer
Journal:  Surg Gynecol Obstet       Date:  1977-05
  10 in total
  2 in total

1.  Chronic Low Dose Prostaglandin and Neonatal Heart Block.

Authors:  Safwat A Aly; Sawsan M Awad; Ra-Id Abdulla; Suhaib Kazmouz; Hoang H Nguyen
Journal:  Pediatr Cardiol       Date:  2017-05-16       Impact factor: 1.655

2.  Prostacyclin as an endogenous anti-arrhythmic agent.

Authors:  U N Das
Journal:  Basic Res Cardiol       Date:  1983 Nov-Dec       Impact factor: 17.165
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.