| Literature DB >> 7001480 |
E E Slater, R Defendini, E A Zimmerman.
Abstract
By use of the indirect peroxidase-antiperoxidase complex immunocytochemical technique, antibody to purified human renal renin was applied to formalin-fixed paraffin sections of human cadaver brain. Immune reaction products were observed in most nerve cells in all areas of the brain examined; staining was limited to the soma and proximal dendrites. These experiments have confirmed the presence of a renin-like substance in central nervous tissue and suggest a more generalized function for "brain renin" than was previously anticipated.Entities:
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Year: 1980 PMID: 7001480 PMCID: PMC350079 DOI: 10.1073/pnas.77.9.5458
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205