Literature DB >> 7000755

Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally.

G B Kohlhaw, Y P Hsu, R D Lemmon, T D Petes.   

Abstract

The repression of beta-isopropylmalate dehydrogenase, the LEU2 gene product, by leucine and leucine plus threonine was unaffected by the transposition of LEU2 from its original locus on chromosome III to a new locus within the ribosomal deoxyribonucleic acid gene cluster on chromosome XII. Since the expression of the LEU2 gene is probably controlled at a pretranslational level, we conclude that the recombinant plasmid used for transformation carries regulatory information in addition to LEU2 structural information.

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Year:  1980        PMID： 7000755      PMCID： PMC294742          DOI： 10.1128/jb.144.2.852-855.1980

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  12 in total

1.  Biosynthesis of branched-chain amino acids in yeast: effect of carbon source on leucine biosynthetic enzymes.

Authors:  H D Brown; T Satyanarayana; H E Umbarger
Journal:  J Bacteriol       Date:  1975-03       Impact factor: 3.490

2.  The expression of cloned eukaryotic DNA in prokaryotes.

Authors:  J Carbon; B Ratzkin; L Clarke; D Richardson
Journal:  Brookhaven Symp Biol       Date:  1977 May 12-20

3.  Separation and quantitation of lactic dehydrogenase isoenzymes by disc electrophoresis.

Authors:  A A Dietz; T Lubrano
Journal:  Anal Biochem       Date:  1967-08       Impact factor: 3.365

4.  Insertion of a genetic marker into the ribosomal DNA of yeast.

Authors:  J W Szostak; R Wu
Journal:  Plasmid       Date:  1979-10       Impact factor: 3.466

5.  Functional expression of cloned yeast DNA in Escherichia coli.

Authors:  B Ratzkin; J Carbon
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

6.  Meiotic mapping of yeast ribosomal deoxyribonucleic acid on chromosome XII.

Authors:  T D Petes
Journal:  J Bacteriol       Date:  1979-04       Impact factor: 3.490

7.  Yeast ribosomal DNA genes are located on chromosome XII.

Authors:  T D Petes
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

8.  Transformation of yeast.

Authors:  A Hinnen; J B Hicks; G R Fink
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

9.  Biosynthesis of branched-chain amino acids in yeast: regulation of leucine biosynthesis in prototrophic and leucine auxotrophic strains.

Authors:  T Satyanarayana; H E Umbarger; G Lindegren
Journal:  J Bacteriol       Date:  1968-12       Impact factor: 3.490

10.  Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes.

Authors:  T D Petes
Journal:  Cell       Date:  1980-03       Impact factor: 41.582
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  7 in total

1.  The upstream activating sequence for L-leucine gene regulation in Saccharomyces cerevisiae.

Authors:  H Tu; M J Casadaban
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

Review 2.  Leucine biosynthesis in fungi: entering metabolism through the back door.

Authors:  Gunter B Kohlhaw
Journal:  Microbiol Mol Biol Rev       Date:  2003-03       Impact factor: 11.056

3.  Cloning and expression analysis of beta-isopropylmalate dehydrogenase from potato.

Authors:  S D Jackson; U Sonnewald; L Willmitzer
Journal:  Mol Gen Genet       Date:  1993-01

4.  Evidence that alpha-isopropylmalate synthase of Saccharomyces cerevisiae is under the "general" control of amino acid biosynthesis.

Authors:  Y P Hsu; G B Kohlhaw; P Niederberger
Journal:  J Bacteriol       Date:  1982-05       Impact factor: 3.490

5.  Evolution of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae.

Authors:  Kerstin Helmstaedt; Axel Strittmatter; William N Lipscomb; Gerhard H Braus
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-29       Impact factor: 11.205

6.  The presence of a defective LEU2 gene on 2 mu DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number.

Authors:  E Erhart; C P Hollenberg
Journal:  J Bacteriol       Date:  1983-11       Impact factor: 3.490

7.  Fusion of the Saccharomyces cerevisiae leu2 gene to an Escherichia coli beta-galactosidase gene.

Authors:  A E Martinez-Arias; M J Casadaban
Journal:  Mol Cell Biol       Date:  1983-04       Impact factor: 4.272
  7 in total

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