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Literature DB >> 7000710

Mutagenicity of aerosols from the oxidative thermal decomposition of rigid polyurethane foam.

Abstract

The aerosol fraction of the oxidative thermal decomposition products (700 degrees C) of rigid polyurethane foam was collected on glass fiber filters and fractionated into either-soluble neutral, acidic, and basic fractions and water-soluble compounds. The fractions showed mutagenic activity in a bacterial fluctuation test with Salmonella typhimurium TA98 or Escherichia coli CM891 as the tester strains. All the fractions induced mutations in both strains after metabolic activation with rat liver S-9 mix. The basic and the water-soluble fractions were mutagenic for S. typhimurium TA 98 even without activation. Thin-layer chromatography showed the presence of several primary aromatic amines in the aerosol. Polycyclic aromatic hydrocarbons were not detected by glass capillary gas chromatogaphy.

Entities: Chemical Species

Mesh：

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Year: 1980 PMID： 7000710 DOI： 10.1007/bf00378327

Source DB: PubMed Journal: Int Arch Occup Environ Health ISSN： 0340-0131 Impact factor: 3.015

17 in total

1. Toxicity of combustion products with particular reference to polyurethane.

Authors: G Kimmerle
Journal: Ann Occup Hyg Date: 1976-12

2. Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

Authors: J McCann; N E Spingarn; J Kobori; B N Ames
Journal: Proc Natl Acad Sci U S A Date: 1975-03 Impact factor: 11.205

3. [Emission of alkylating compounds during the burning process].

Authors: K Norpoth; G Manegold; R Brücker; H P Amann
Journal: Zentralbl Bakteriol Orig B Date: 1972-12

4. Carcinogenic and chronic effects of 4,4'-diaminodiphenylmethane, an epoxyresin hardener.

Authors: R Schoental
Journal: Nature Date: 1968-09-14 Impact factor: 49.962

5. Isocyanate hazard from wire insulation: an old hazard in a new guise.

Authors: D P Paisley
Journal: Br J Ind Med Date: 1969-01

6. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

Authors: B N Ames; J Mccann; E Yamasaki
Journal: Mutat Res Date: 1975-12 Impact factor: 2.433

7. Mutagen screening by a simplified bacterial fluctuation test: use of microsomal preparations and whole liver cells for metabolic activation.

Authors: M H Green; B A Bridges; A M Rogers; G Horspool; W J Muriel; J W Bridges; J R Fry
Journal: Mutat Res Date: 1977-07 Impact factor: 2.433

Mutagenicity of aerosols from the oxidative thermal decomposition of rigid polyurethane foam.

1. Toxicity of combustion products with particular reference to polyurethane.

2. Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

3. [Emission of alkylating compounds during the burning process].

4. Carcinogenic and chronic effects of 4,4'-diaminodiphenylmethane, an epoxyresin hardener.

5. Isocyanate hazard from wire insulation: an old hazard in a new guise.

6. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

7. Mutagen screening by a simplified bacterial fluctuation test: use of microsomal preparations and whole liver cells for metabolic activation.

Review 8. Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.

9. Mutagenic activity in foundry air.

10. Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides, and disulfides.

1. Cancer incidence among firefighters in Seattle and Tacoma, Washington (United States).