Literature DB >> 700028

Chemical and photooxidation of thiothixene (Navane): structure of the thiothixene fluorophor.

L E Eiden, J A Ruth.   

Abstract

The spontaneous photooxidation of thiothixen (Navane) to 2-(N,N-dimethyl-sulfonamido)-9-thioxanthone is described. The corresponding sulfoxide is demonstrated to be the fluorescent species obtained upon permanganate oxidation of thiothixene in the fluorometric assay procedure of Mjörndal and Oreland.

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Year:  1978        PMID: 700028     DOI: 10.1007/bf01915349

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  3 in total

1.  Determination of thioxanthenes in plasma at therapeutic concentrations.

Authors:  T Mjörndal; L Oreland
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1971

2.  Thioxanthene psychopharmacological agents. II. 9-(3-aminopropylidene)-N,N-dimethylthioxanthene-2-sulfonamides.

Authors:  J F Muren; B M Bloom
Journal:  J Med Chem       Date:  1970-01       Impact factor: 7.446

3.  A method for the fluorimetric determination of thioridazine (Mellaril) or mesoridazine (Lidanil) in plasma.

Authors:  W L Pacha
Journal:  Experientia       Date:  1969-01-15
  3 in total
  1 in total

1.  Colorimetric determination of thioxanthenes with tetracyanoethylene.

Authors:  M I Walash; M Rizk; A el-Brashy
Journal:  Pharm Weekbl Sci       Date:  1986-08-22
  1 in total

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