Literature DB >> 700013

Increased blood pressure in the SHR is not related to a deficit in renomedullary PGE2.

V G Stygles, D A Reinke, D E Rickert, J B Hook.   

Abstract

Synthesis of prostaglandin E2 by renal medulla from SHR and WKY rats was compared during early postnatal development. Although arterial blood pressure was significantly higher in SHR as early as 6 weeks of age, no difference in renal medullary prostaglandin synthesis was observed.

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Year:  1978        PMID: 700013     DOI: 10.1007/bf01915324

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  Renomedullary deficiency. A contributory factor in the pathogenesis of experimental renal hypertension.

Authors:  D Susic; J C Sparks; E A Machado
Journal:  Experientia       Date:  1976-03-15

2.  Renal prostaglandin synthesis in the Goldblatt hypertensive rat.

Authors:  D J Pugsley; L J Beilin; R Peto
Journal:  Circ Res       Date:  1975-06       Impact factor: 17.367

Review 3.  The inter-relationships between renal prostaglandins and blood pressure regulation.

Authors:  J B Lee
Journal:  Am J Med Sci       Date:  1972-05       Impact factor: 2.378

4.  Release of renomedullary prostaglandins in normal and hypertensive rats.

Authors:  P Sirois; D J Gagnon
Journal:  Experientia       Date:  1974-12-15

5.  Relative activity of prostaglandins E1, A1, E2 and A2 on lipolysis, platelet aggregation, smooth muscle and the cardiovascular system.

Authors:  J R Weeks; N C Sekhar; D W Ducharme
Journal:  J Pharm Pharmacol       Date:  1969-02       Impact factor: 3.765

6.  Prostaglandins in rat tissues.

Authors:  N Papanicolaou; S Makrakis; J Bariety; P Milliez
Journal:  J Pharm Pharmacol       Date:  1974-04       Impact factor: 3.765

7.  Modulation by prostaglandins of adrenergic transmission in the isolated perfused rabbit and rat kidney.

Authors:  K U Malik; J C McGiff
Journal:  Circ Res       Date:  1975-05       Impact factor: 17.367

8.  Prostaglandin E2 production by renomedullary tissue of DOCA, Goldblatt and spontaneously hypertensive rats.

Authors:  V G Stygles; D A Reinke; J B Hook
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1976-12

9.  Renal prostaglandin synthesis in the spontaneously hypertensive rat.

Authors:  M J Dunn
Journal:  J Clin Invest       Date:  1976-10       Impact factor: 14.808

10.  Decreased renal prostaglandin catabolism precedes onset of hypertension in the developing spontaneously hypertensive rat.

Authors:  C R Pace-Asciak
Journal:  Nature       Date:  1976-10-07       Impact factor: 49.962

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