Literature DB >> 700011

Microbiological oxidation of the pentyl side chain of cannabinoids.

L W Robertson, S W Koh, S R Huff, R K Malhotra, A Ghosh.   

Abstract

Syncephalastrum racemosum ATCC 18192 and Mycobacterium rhodochrous ATCC 19067 partially degrade the n-pentyl side chain of cannabidiol, cannabinol, delta8-tetrahydrocannabinol and delta9-tetrahydrocannabinol. Carboxylic acid and alcohol side chain derivatives are major metabolites.

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Year:  1978        PMID： 700011     DOI： 10.1007/bf01915321

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  Identification of new in vivo side-chain acid metabolites of delta1-tetrahydrocannabinol.

Authors:  B R Martin; D J Harvey; W D Paton
Journal:  J Pharm Pharmacol       Date:  1976-10       Impact factor: 3.765

2.  Microbiological transformation of cannabinoids.

Authors:  B J Abbott; D S Fukuda; R A Archer
Journal:  Experientia       Date:  1977-06-15

3.  Identification of monohydroxylated metabolites of cannabidiol formed by rat liver.

Authors:  B Martin; M Nordqvist; S Agurell; J E Lindgren; K Leander; M Binder
Journal:  J Pharm Pharmacol       Date:  1976-04       Impact factor: 3.765

4.  Dioxygenated metabolites of cannabidiol formed by rat liver.

Authors:  B Martin; S Agurell; M Nordqvist; J E Lindgren
Journal:  J Pharm Pharmacol       Date:  1976-08       Impact factor: 3.765

5.  Biotransformation of cannabidiol in mice. Identification of new acid metabolites.

Authors:  B R Martin; D J Harvey; W D Paton
Journal:  Drug Metab Dispos       Date:  1977 May-Jun       Impact factor: 3.922

6.  Transformations of cannabinol in the mouse.

Authors:  S Burstein; C Varanelli
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1975-07
  6 in total
  5 in total

1.  Microbiological transformations of nabilone, a synthetic cannabinoid.

Authors:  R A Archer; D S Fukuda; A D Kossoy; B J Abbott
Journal:  Appl Environ Microbiol       Date:  1979-05       Impact factor: 4.792

2.  In vitro stability of free and glucuronidated cannabinoids in urine following controlled smoked cannabis.

Authors:  Nathalie A Desrosiers; Dayong Lee; Karl B Scheidweiler; Marta Concheiro-Guisan; David A Gorelick; Marilyn A Huestis
Journal:  Anal Bioanal Chem       Date:  2013-12-01       Impact factor: 4.142

3.  Hydroxylation and further oxidation of delta9-tetrahydrocannabinol by alkane-degrading bacteria.

Authors:  Hassan Rashidi; Muhammad T Akhtar; Frank van der Kooy; Robert Verpoorte; Wouter A Duetz
Journal:  Appl Environ Microbiol       Date:  2009-09-18       Impact factor: 4.792

4.  Metabolism of cannabidiol by the rat.

Authors:  E Samara; M Bialer; D J Harvey
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1991 Oct-Dec       Impact factor: 2.441

Review 5.  Human Metabolites of Cannabidiol: A Review on Their Formation, Biological Activity, and Relevance in Therapy.

Authors:  István Ujváry; Lumír Hanuš
Journal:  Cannabis Cannabinoid Res       Date:  2016-03-01
  5 in total

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