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Literature DB >> 700002

The effect of pentobarbital, chloralhydrate, ether and protoveratrine on the distribution of synaptic vesicles in rat cortical synaptosomes.

Abstract

Rat cortical synaptosomes were incubated in a saline medium. On the addition of pentobarbital, chloralhydrate, ether and protoveratrine a redistribution of synaptic vesicles was revealed by electron microscopy. The anaesthetics decreased the number of synaptic vesicles attached to the presynaptic membrane while protoveratrine increased them. It is assumed that these agents affect the mechanism of vesicle reformation from the synaptosomal membrane and/or vesicle migration towards the synaptic cleft.

Entities: Chemical Species

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Year: 1978 PMID： 700002 DOI： 10.1007/bf00238797

Source DB: PubMed Journal: Exp Brain Res ISSN： 0014-4819 Impact factor: 1.972

21 in total

1. An improved method for the preparation of synaptosomal fractions in high purity.

Authors: F Hajós
Journal: Brain Res Date: 1975-08-15 Impact factor: 3.252

2. SITE OF ACTION OF THIAMYLAL SODIUM ON THE MONOSYNAPTIC SPINAL REFLEX PATHWAY IN CATS.

Authors: Y LOYNING; T OSHIMA; T YOKOTA
Journal: J Neurophysiol Date: 1964-05 Impact factor: 2.714

3. Structural changes in vitro of isolated nerve endings. I. Effect of cations.

Authors: F Hajós; A Csillag
Journal: Brain Res Date: 1976-08-06 Impact factor: 3.252

4. Local vesicle populations in rat superior cervical ganglia and the vesicle hypothesis.

Authors: J P Quilliam; D L Tamarind
Journal: J Neurocytol Date: 1973-03

5. Effect of barbiturates on 'quantal' synaptic transmission in spinal motoneurones.

Authors: J N Weakly
Journal: J Physiol Date: 1969-09 Impact factor: 5.182

6. Depolarizing stimuli and the release of physiologically active amino acids from suspensions of mammalian synaptosomes.

Authors: H F Bradford; G W Bennett; A J Thomas
Journal: J Neurochem Date: 1973-09 Impact factor: 5.372

10. Synaptic vesicle depletion and recovery in cat sympathetic ganglia electrically stimulated in vivo. Evidence for transmitter secretion by exocytosis.

Authors: J J Pysh; R G Wiley
Journal: J Cell Biol Date: 1974-02 Impact factor: 10.539

3 in total

The effect of pentobarbital, chloralhydrate, ether and protoveratrine on the distribution of synaptic vesicles in rat cortical synaptosomes.

1. An improved method for the preparation of synaptosomal fractions in high purity.

2. SITE OF ACTION OF THIAMYLAL SODIUM ON THE MONOSYNAPTIC SPINAL REFLEX PATHWAY IN CATS.

3. Structural changes in vitro of isolated nerve endings. I. Effect of cations.

4. Local vesicle populations in rat superior cervical ganglia and the vesicle hypothesis.

5. Effect of barbiturates on 'quantal' synaptic transmission in spinal motoneurones.

6. Depolarizing stimuli and the release of physiologically active amino acids from suspensions of mammalian synaptosomes.

7. The osmotically sensitive potassium and sodium compartments of synaptosomes.

8. The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb.

9. Turnover of transmitter and synaptic vesicles at the frog neuromuscular junction.

10. Synaptic vesicle depletion and recovery in cat sympathetic ganglia electrically stimulated in vivo. Evidence for transmitter secretion by exocytosis.

1. Pentobarbitone interference with inhibitory synaptic transmission in crayfish stretch receptor neurones.

2. The effect of gamma-aminobutyric acid on the potassium movements of rat cortical synaptosomes.

3. Synaptic terminal parameters in unanesthetized rat cerebral cortex.