Literature DB >> 699957

Expression of HLA-A, but not of HLA-B, in mouse-human somatic cell hybrids carrying the region p21 leads to pter of human chromosome 6.

C M Zmijewski, E Engel, C M Croce.   

Abstract

Mouse-human somatic cell hybrids containing human chromosome 17 carrying the region p21 leads to pter of human chromosome 6 and no other human chromosomes, were found to express HLA-A but not HLA-B. Counterselection of the hybrid cells in medium containing 5-bromodeoxyuridine resulted in the growth of hybrid cells that have concordantly lost the expression of HLA-A and the human translocation chromosome.

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Year:  1978        PMID: 699957     DOI: 10.1002/eji.1830080814

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN: 0014-2980            Impact factor:   5.532


  3 in total

1.  The gene encoding vasoactive intestinal peptide is located on human chromosome 6p21----6qter.

Authors:  I Gozes; R Avidor; Y Yahav; D Katznelson; C M Croce; K Huebner
Journal:  Hum Genet       Date:  1987-01       Impact factor: 4.132

2.  The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.

Authors:  L Nagarajan; E Louie; Y Tsujimoto; P C Balduzzi; K Huebner; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

3.  Localization of the human pim oncogene (PIM) to a region of chromosome 6 involved in translocations in acute leukemias.

Authors:  L Nagarajan; E Louie; Y Tsujimoto; A ar-Rushdi; K Huebner; C M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

  3 in total

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