Literature DB >> 6999120

Phenotypic resistance to miconazole and amphotericin B in Candida albicans.

E F Gale, A M Johnson, D Kerridge, F Wayman.   

Abstract

Phenotypic resistance to both amphotericin B and miconazole develops in stationary phase cultures of Candida albicans and this resistance lies in changes in the cell wall. Study of the effects of growth conditions, treatment with SH-reactive agents and treatment with enzymes indicates that the nature of the changes leading to resistance must be different for the two drugs.

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Year:  1980        PMID： 6999120     DOI： 10.1099/00221287-117-2-535

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN： 0022-1287


  2 in total

1.  High-frequency, in vitro reversible switching of Candida lusitaniae clinical isolates from amphotericin B susceptibility to resistance.

Authors:  S A Yoon; J A Vazquez; P E Steffan; J D Sobel; R A Akins
Journal:  Antimicrob Agents Chemother       Date:  1999-04       Impact factor: 5.191

2.  In vitro interaction between amphotericin B and azoles in Candida albicans.

Authors:  J A Vazquez; M T Arganoza; J K Vaishampayan; R A Akins
Journal:  Antimicrob Agents Chemother       Date:  1996-11       Impact factor: 5.191
  2 in total

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