Literature DB >> 6998804

Different effects of hypothermia on insulin and glucagon secretion from the isolated perfused rat pancreas.

M M Loubatières-Mariani, J Chapal, R Puech, F Lignon, G Valette.   

Abstract

Two series of experiments with the isolated perfused rat pancreas were performed in parallel. The conditions differed only with respect to temperature, which was 37.5 degrees C in one series and 28 degrees C in the other. The lowering of the temperature decreased insulin secretion induced by glucose as well as the insulin response to tolbutamide and acetylcholine. Unlike insulin, glucagon secretion was not significantly modified by hypothermia. Our results suggest that the mechanisms involved in glucagon and insulin secretion are different.

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Year:  1980        PMID： 6998804     DOI： 10.1007/bf00251015

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  14 in total

1.  EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS.

Authors:  G M GRODSKY; A A BATTS; L L BENNETT; C VCELLA; N B MCWILLIAMS; D F SMITH
Journal:  Am J Physiol       Date:  1963-10

2.  Immunoassay of insulin with insulin-antibody precipitate.

Authors:  C N HALES; P J RANDLE
Journal:  Biochem J       Date:  1963-07       Impact factor: 3.857

3.  Temperature effects on the modulation of adenylate cyclases from rat liver and Morris hepatomas.

Authors:  T K Pradhan; W E Criss
Journal:  Oncology       Date:  1977       Impact factor: 2.935

4.  Calcium, glucose and glucagon release.

Authors:  J Iversen; K Hermansen
Journal:  Diabetologia       Date:  1977-08       Impact factor: 10.122

5.  Studies on the dual effects of glucose on 45Ca++ efflux from isolated rat islets.

Authors:  M Kikuchi; C B Wollheim; G S Cuendet; A E Renold; G W Sharp
Journal:  Endocrinology       Date:  1978-05       Impact factor: 4.736

6.  Calcium dependency of glucagon secretion from the in vitro perfused rat pancreas.

Authors:  J E Gerich; B J Frankel; R Fanska; L West; P H Forsham; G M Grodsky
Journal:  Endocrinology       Date:  1974-05       Impact factor: 4.736

7.  Hypothermia and insulin secretion.

Authors:  D L Curry; K P Curry
Journal:  Endocrinology       Date:  1970-10       Impact factor: 4.736

8.  Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro.

Authors:  H G Coore; P J Randle
Journal:  Biochem J       Date:  1964-10       Impact factor: 3.857

9.  Interrelationship of islet metabolism, adenosine triphosphate content and insulin release.

Authors:  S J Ashcroft; L C Weerasinghe; P J Randle
Journal:  Biochem J       Date:  1973-02       Impact factor: 3.857

10.  Investigations on isolated islets of langerhans in vitro. 16.Modification of the glucose-dependent inhibition of glucagon secretion.

Authors:  H J Hahn; M Ziegler
Journal:  Biochim Biophys Acta       Date:  1977-10-25
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  3 in total

1.  Ex situ Perfusion of Pancreas for Whole-Organ Transplantation: Is it Safe and Feasible? A Systematic Review.

Authors:  Thomas Prudhomme; Delphine Kervella; Stéphanie Le Bas-Bernardet; Diego Cantarovich; Georges Karam; Gilles Blancho; Julien Branchereau
Journal:  J Diabetes Sci Technol       Date:  2019-08-13

2.  Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization.

Authors:  E Renström; L Eliasson; K Bokvist; P Rorsman
Journal:  J Physiol       Date:  1996-07-01       Impact factor: 5.182

3.  Pancreatic A and B cell stimulation in euthermic and hibernating marmots (Marmota flaviventris): effects of glucose and arginine administration.

Authors:  G L Florant; R Hoo-Paris; C Castex; W A Bauman; B C Sutter
Journal:  J Comp Physiol B       Date:  1986       Impact factor: 2.200
  3 in total

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