Literature DB >> 6997042

Regulation of compartmentation of amino acid pools in Saccharomyces cerevisiae and its effects on metabolic control.

F Messenguy, D Colin, J P ten Have.   

Abstract

Compartmentation of intracellular amino acid pools has been studied under various growth conditions in wild-type strains as well as in mutants. Aspartate, glutamate, leucine and isoleucine pools are present in high concentrations in the cytoplasm, while all the other amino acids are more vacuolar. The nature of the nitrogen source for growth, the effectiveness of nitrogen assimilation, the rate of protein synthesis and the presence of high internal basic amino acid pools are important factors in the repartition of amino acid pools between the cytoplasm and the vacuole.

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Year:  1980        PMID: 6997042     DOI: 10.1111/j.1432-1033.1980.tb04740.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  45 in total

1.  Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii.

Authors:  Christina Schlüpen; Maria A Santos; Ulrike Weber; Albert de Graaf; José L Revuelta; K-Peter Stahmann
Journal:  Biochem J       Date:  2003-01-15       Impact factor: 3.857

2.  Role of the complex upstream region of the GDH2 gene in nitrogen regulation of the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae.

Authors:  S M Miller; B Magasanik
Journal:  Mol Cell Biol       Date:  1991-12       Impact factor: 4.272

3.  Synthetic cooperation in engineered yeast populations.

Authors:  Wenying Shou; Sri Ram; Jose M G Vilar
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-31       Impact factor: 11.205

4.  Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2p.

Authors:  John M Zaborske; Jana Narasimhan; Li Jiang; Sheree A Wek; Kimberly A Dittmar; Florien Freimoser; Tao Pan; Ronald C Wek
Journal:  J Biol Chem       Date:  2009-06-22       Impact factor: 5.157

5.  Vacuole partitioning during meiotic division in yeast.

Authors:  A D Roeder; J M Shaw
Journal:  Genetics       Date:  1996-10       Impact factor: 4.562

6.  Biological role of the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

Authors:  P Niederberger; G Miozzari; R Hütter
Journal:  Mol Cell Biol       Date:  1981-07       Impact factor: 4.272

Review 7.  Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

Authors:  A G Hinnebusch
Journal:  Microbiol Rev       Date:  1988-06

8.  Amino acids regulate the intracellular trafficking of the general amino acid permease of Saccharomycescerevisiae.

Authors:  Esther J Chen; Chris A Kaiser
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-04       Impact factor: 11.205

9.  The PEP4 gene encodes an aspartyl protease implicated in the posttranslational regulation of Saccharomyces cerevisiae vacuolar hydrolases.

Authors:  C A Woolford; L B Daniels; F J Park; E W Jones; J N Van Arsdell; M A Innis
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272

10.  Suppression of metabolic defects of yeast isocitrate dehydrogenase and aconitase mutants by loss of citrate synthase.

Authors:  An-Ping Lin; Kevin W Hakala; Susan T Weintraub; Lee McAlister-Henn
Journal:  Arch Biochem Biophys       Date:  2008-03-10       Impact factor: 4.013

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