Literature DB >> 6996034

Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia.

G Remuzzi, D Marchesi, C Zoja, D Muratore, G Mecca, R Misiani, E Rossi, M Barbato, P Capetta, M B Donati, G de Gaetano.   

Abstract

Prostacyclin production was significantly depressed in foetal and placental vascular tissues from five patients with severe pre-eclampsia in comparison to vascular tissues from women with uncomplicated pregnancy. Such an abnormality may be responsible for a reduced blood flow and defective fetal nutrition thus playing a major role in the pathogenesis of this syndrome.

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Year:  1980        PMID: 6996034     DOI: 10.1016/0090-6980(80)90010-6

Source DB:  PubMed          Journal:  Prostaglandins        ISSN: 0090-6980


  21 in total

1.  Placental Production of Eicosanoids and Sphingolipids in Women Who Developed Preeclampsia on Low-Dose Aspirin.

Authors:  Scott W Walsh; Daniel T Reep; S M Khorshed Alam; Sonya L Washington; Marwah Al Dulaimi; Stephanie M Lee; Edward H Springel; Jerome F Strauss; Daniel J Stephenson; Charles E Chalfant
Journal:  Reprod Sci       Date:  2020-06-17       Impact factor: 3.060

2.  Abnormalities of vascular prostaglandins in Henoch-Schönlein purpura.

Authors:  S Turi; J J Belch; T J Beattie; C D Forbes
Journal:  Arch Dis Child       Date:  1986-02       Impact factor: 3.791

3.  Alternative mechanisms for the hypotensive effects of adrenergic blockade.

Authors:  I A Greer; J J Walker; M McLaren; J J Belch; A A Calder; C D Forbes
Journal:  Br Med J (Clin Res Ed)       Date:  1983-11-19

4.  Plasmatic regulation of vascular prostacyclin in pregnancy.

Authors:  G Remuzzi; C Zoja; D Marchesi; A Schieppati; G Mecca; R Misiani; M B Donati; G de Gaetano
Journal:  Br Med J (Clin Res Ed)       Date:  1981-02-14

5.  Kinetics of prostacyclin synthetase in umbilical artery microsomes from normal and pre-eclamptic pregnancies.

Authors:  I Downing; G L Shepherd; P J Lewis
Journal:  Br J Clin Pharmacol       Date:  1982-02       Impact factor: 4.335

6.  Central venous concentrations of immunoreactive prostaglandins E, F, and 6-keto-prostaglandin F1 in eclampsia.

Authors:  J Moodley; R J Norman; K Reddi
Journal:  Br Med J (Clin Res Ed)       Date:  1984-05-19

7.  Plasma factors influencing PGI2-like activity in patients with IgA nephropathy and Henoch-Schönlein purpura.

Authors:  S Túri; J Nagy; I Haszon; Z Havass; M Németh; C Bereczki
Journal:  Pediatr Nephrol       Date:  1989-01       Impact factor: 3.714

Review 8.  Protein nitration in placenta - functional significance.

Authors:  R P Webster; V H J Roberts; L Myatt
Journal:  Placenta       Date:  2008-10-11       Impact factor: 3.481

9.  Effect of prostacyclin on the perfusion pressure and on the vasoconstrictor response of angiotensin II in the human isolated foetal placental circulation.

Authors:  R Soares de Moura
Journal:  Br J Clin Pharmacol       Date:  1987-06       Impact factor: 4.335

10.  In vitro activity of nicotinamide adenine dinucleotide- and nicotinamide adenine dinucleotide phosphate-linked 15-hydroxyprostaglandin dehydrogenases in placentas from normotensive and preeclamptic/eclamptic pregnancies.

Authors:  J Jarabak; J D Watkins; M Lindheimer
Journal:  J Clin Invest       Date:  1987-10       Impact factor: 14.808

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