Literature DB >> 6995360

Organized nerve culture. II. DNA synthesis in Schwann cells in the presence of M. leprae.

R Mukherjee, P R Mahadevan, N H Antia.   

Abstract

Schwann cells that contain M. leprae fail to incorporate DNA precursor, indicating blockage of DNA synthesis. Such a block could lead to no proliferation of Schwann cells, an essential requirement for successful association with axons and consequent myelination.

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Year:  1980        PMID: 6995360

Source DB:  PubMed          Journal:  Int J Lepr Other Mycobact Dis        ISSN: 0148-916X


  2 in total

1.  Expression of major histocompatibility complex class I and class II antigens in human Schwann cell cultures and effects of infection with Mycobacterium leprae.

Authors:  N M Samuel; R Mirsky; J M Grange; K R Jessen
Journal:  Clin Exp Immunol       Date:  1987-06       Impact factor: 4.330

2.  Intracellular multiplication of leprosy-derived mycobacteria in Schwann cells of dorsal root ganglion cultures.

Authors:  R Mukherjee; N H Antia
Journal:  J Clin Microbiol       Date:  1985-05       Impact factor: 5.948

  2 in total

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