Literature DB >> 69937

A membrane-bound enzyme in rabbit aorta capable of inhibiting adenosine-diphosphate-induced platelet aggregation.

G E Lieberman, G P Lewis, T J Peters.   

Abstract

A membrane-bound enzyme that is capable of inhibiting adenosine-diphosphate (A.D.P.)-induced platelet aggregation has been found in rabbit aorta. This inhibition is caused by degradation of A.D.P. to products (adenosine monophosphate and adenosine) which can also inhibit aggregation. The enzyme could be important in regulating haemostasis and thrombosis.

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Year:  1977        PMID: 69937     DOI: 10.1016/s0140-6736(77)91488-x

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  19 in total

1.  Enzyme activities in endothelial cells and smooth muscle cells from swine aorta.

Authors:  L W Hayes; C A Goguen; A L Stevens; W W Magargal; L L Slakey
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

2.  Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase. Thromboregulation by endothelial cells.

Authors:  A J Marcus; L B Safier; K A Hajjar; H L Ullman; N Islam; M J Broekman; A M Eiroa
Journal:  J Clin Invest       Date:  1991-11       Impact factor: 14.808

3.  [Significance of the endothelium of the vascular wall for maintaining hemostasis].

Authors:  U Delvos; G Müller-Berghaus
Journal:  Klin Wochenschr       Date:  1985-12-16

Review 4.  Extracellular ATP: effects, sources and fate.

Authors:  J L Gordon
Journal:  Biochem J       Date:  1986-01-15       Impact factor: 3.857

Review 5.  The vascular endothelium-pathobiologic significance.

Authors:  G Thorgeirsson; A L Robertson
Journal:  Am J Pathol       Date:  1978-12       Impact factor: 4.307

Review 6.  Platelet responses in health and disease.

Authors:  M I Barnhart
Journal:  Mol Cell Biochem       Date:  1978-12-22       Impact factor: 3.396

7.  Studies on the kinetic properties and subcellular localization of adenine nucleotide phosphatases in peripheral blood lymphocytes from control subjects and patients with common variable primary hypogammaglobulinaemia.

Authors:  G P Smith; T Shah; A D Webster; T J Peters
Journal:  Clin Exp Immunol       Date:  1982-08       Impact factor: 4.330

8.  Electron microscopic cytochemical localization of nucleoside phosphatases in normal and chronic granulocytic leukaemic human neutrophils.

Authors:  P D Wilson; G J Rustin; G P Smith; T J Peters
Journal:  Histochem J       Date:  1981-01

9.  Effects of aspirin and dipyridamole on the degradation of adenosine diphosphate by cultured cells derived from bovine pulmonary artery.

Authors:  D J Crutchley; U S Ryan; J W Ryan
Journal:  J Clin Invest       Date:  1980-07       Impact factor: 14.808

10.  Effect of streptozotocin-induced diabetes on the metabolism of ADP, AMP and adenosine in the pulmonary circulation of rat isolated lung.

Authors:  Y S Bakhle; R Chelliah
Journal:  Diabetologia       Date:  1983-06       Impact factor: 10.122

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