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Literature DB >> 6991399

Endotoxin-induced appearance of peroxidase-positive cells in the white pulp of the mouse spleen.

Abstract

Endotoxin (1-10 microgram intravenously) increased the number of strongly peroxidase-positive cells in the white pulp of the mouse spleen, demonstrable by the Graham-Karnovsky technique. The increase was greatest after 10 h, the cells being found most frequently around the central vessels of the white pulp. The appearance of such cells at this critical immunological site may relate to the known adjuvant activity of endotoxin in promoting immune responses against protein antigens.

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Year: 1980 PMID： 6991399 PMCID： PMC1458014

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

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References

19 in total

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Authors: M A Stahmann; A K Spencer
Journal: Biopolymers Date: 1977-06 Impact factor: 2.505

2. The role of lymphocytes in antibody formation. II. The influence of lymphocyte migration on the initiation of antibody formation in the isolated, perfused spleen.

Authors: W L Ford; J L Gowans
Journal: Proc R Soc Lond B Biol Sci Date: 1967-09-12

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Authors: R N Taub; A R Krantz; D W Dresser
Journal: Immunology Date: 1970-02 Impact factor: 7.397

4. A study of the localisation of a protein antigen in the chicken spleen and its relation to the formation of germinal centres.

Authors: R G White; V I French; J M Stark
Journal: J Med Microbiol Date: 1970-02 Impact factor: 2.472

9. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.

Authors: R C Graham; M J Karnovsky
Journal: J Histochem Cytochem Date: 1966-04 Impact factor: 2.479

10. The immunogenicity of antigen bound to the plasma membrane of macrophages.

Authors: E R Unanue; J C Cerottini
Journal: J Exp Med Date: 1970-04-01 Impact factor: 14.307

Endotoxin-induced appearance of peroxidase-positive cells in the white pulp of the mouse spleen.

1. Cross linking of proteins in vitro by peroxidase.

2. The role of lymphocytes in antibody formation. II. The influence of lymphocyte migration on the initiation of antibody formation in the isolated, perfused spleen.

3. The effect of localized injection of adjuvant material on the draining lymph node. I. Histology.

4. A study of the localisation of a protein antigen in the chicken spleen and its relation to the formation of germinal centres.

5. A role of macrophages in the stimulation of immune responses by adjuvants.

6. Functional anatomy of lymph nodes. I. The paracortical cords.

7. Functional anatomy of lymph nodes. II. Peripheral lymph-borne mononuclear cells.

8. Immunogenicity of lipid-conjugated antigens. II. Anti-complementary activity and antigen trapping in the spleen.

9. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.

10. The immunogenicity of antigen bound to the plasma membrane of macrophages.