Literature DB >> 6990951

Uptake of aggregated immunoglobulin by the mouse kidney. I. Effect of endotoxin.

Y Shvil, A F Michael, S M Mauer.   

Abstract

Endotoxin (ET) pretreatment of mice resulted in increased liver and spleen uptake and decreased circulating levels of aggregated IgC (AggIgG) compared to control animals. ET had no effect upon the uptake of AggIgG by lung or whole kidney cortex. However, immunofluorescent microscopy revealed increased localization of AggIgG in the mesangium of ET mice at 1 but not at 2 or 16 h after administration of AggIgG. These studies show that mesangial macromolecular uptake is not solely dependent upon blood levels, but appears to be influenced by unknown and probably complex variables.

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Year:  1980        PMID： 6990951      PMCID： PMC2041558     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  17 in total

1.  Effect of cortisone on the disappearance kinetics and tissue localization of soluble immune complexes.

Authors:  A O Haakenstad; J B Case; M Mannik
Journal:  J Immunol       Date:  1975-04       Impact factor: 5.422

2.  The effect of manipulation of reticuloendothelial system activity on glomerular deposition of aggregated protein and immune complexes in two different strains of mice.

Authors:  P M Ford
Journal:  Br J Exp Pathol       Date:  1975-12

3.  Glomerular localization and transport of aggregated proteins in mice.

Authors:  A F Michael; A J Fish; R A Good
Journal:  Lab Invest       Date:  1967-07       Impact factor: 5.662

4.  Saturation of the reticuloendothelial system with soluble immune complexes.

Authors:  A O Haakenstad; M Mannik
Journal:  J Immunol       Date:  1974-05       Impact factor: 5.422

5.  Increased mitotic activity in rabbit endothelium after endotoxin. An autoradiographic study.

Authors:  E Gaynor
Journal:  Lab Invest       Date:  1971-04       Impact factor: 5.662

6.  The ultrastructure of the juxtaglomerular apparatus as disclosed by three-dimensional reconstructions from serial sections. The anatomical relationship between the tubular and vascular components.

Authors:  L Barajas
Journal:  J Ultrastruct Res       Date:  1970-10

7.  Evidence concerning the origin of liver macrophages.

Authors:  L S Kelly; E L Dobson
Journal:  Br J Exp Pathol       Date:  1971-02

8.  The glomerular mesangium. II. Studies of macromolecular uptake in nephrotoxic nephritis in rats.

Authors:  S M Mauer; A J Fish; N K Day; A F Michael
Journal:  J Clin Invest       Date:  1974-02       Impact factor: 14.808

9.  Glomerular localization of aggregated protein in mice; effect of strain difference and relationship to systemic macrophage function.

Authors:  P M Ford
Journal:  Br J Exp Pathol       Date:  1975-08

10.  The glomerular mesangium. I. Kinetic studies of macromolecular uptake in normal and nephrotic rats.

Authors:  S M Mauer; A J Fish; E B Blau; A F Michael
Journal:  J Clin Invest       Date:  1972-05       Impact factor: 14.808
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  4 in total

1.  The effect of charge on the renal distribution of ferritin.

Authors:  S Cohen; R L Vernier; A F Michael
Journal:  Am J Pathol       Date:  1983-02       Impact factor: 4.307

2.  In vivo effects of lipopolysaccharide on lymphoid and non-lymphoid cells in the mouse spleen. Reduction of T-lymphocytes and phagocytosis in the inner parts of the periarteriolar lymphocyte sheath.

Authors:  P H Groeneveld; N van Rooijen
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

3.  Uptake of aggregated immunoglobulin by the mouse kidney. II. Effect of hydrocortisone.

Authors:  Y Shvil; S M Mauer; A F Michael
Journal:  Br J Exp Pathol       Date:  1980-02

4.  Intravenous immunoglobulin in the management of lupus nephritis.

Authors:  Scott E Wenderfer; Trisha Thacker
Journal:  Autoimmune Dis       Date:  2012-09-27
  4 in total

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