Literature DB >> 6990948

Evaluation of glycopyrrolate and atropine as adjuncts to reversal of non-depolarizing neuromuscular blocking agents in a "true-to-life" situation.

D A Cozanitis, J W Dundee, J D Merrett, C J Jones, R K Mirakhur.   

Abstract

Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease.

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Year:  1980        PMID: 6990948     DOI: 10.1093/bja/52.1.85

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  4 in total

1.  Anaesthetic management of vitrectomy.

Authors:  R K Mirakhur
Journal:  Ann R Coll Surg Engl       Date:  1985-01       Impact factor: 1.891

2.  Proceeding of the British Pharmacological Society, Clinical Pharmacology Section, 16-18th December, 1980, University of London. Abstracts.

Authors: 
Journal:  Br J Clin Pharmacol       Date:  1981-04       Impact factor: 4.335

3.  Dose-response studies on glycopyrrolate and atropine in conscious cardiac patients.

Authors:  D Preiss; P Berguson
Journal:  Br J Clin Pharmacol       Date:  1983-11       Impact factor: 4.335

4.  Prevalence, risk factors, and optimized management of moderate-to-severe thirst in the post-anesthesia care unit.

Authors:  Chia-Wei Lee; Shih-Ting Liu; Ya-Jung Cheng; Ching-Tang Chiu; Yu-Fen Hsu; Anne Chao
Journal:  Sci Rep       Date:  2020-09-30       Impact factor: 4.379

  4 in total

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