| Literature DB >> 6990948 |
D A Cozanitis, J W Dundee, J D Merrett, C J Jones, R K Mirakhur.
Abstract
Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease.Entities:
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Year: 1980 PMID: 6990948 DOI: 10.1093/bja/52.1.85
Source DB: PubMed Journal: Br J Anaesth ISSN: 0007-0912 Impact factor: 9.166