Literature DB >> 699047

Recessive male-determining genes.

S S Wachtel, P Basrur, G C Koo.   

Abstract

The autosomal dominant gene polled (P) causes hornlessness in goats. Chromosomal females (XX) that are P/P homozygotes develop testes or ovotestes. Thus with respect to its testis-determining properties, P or a closely linked gene acts as an autosomal recessive. Polled intersex goats are H-Y+. This finding is consistent with the view that there may be a cluster of testis-determining H-Y genes on the Y chromosome, and that translocation of a subcritical portion of these genes may generate a recessive mode of sex determination.

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Year:  1978        PMID: 699047     DOI: 10.1016/0092-8674(78)90103-4

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  21 in total

1.  XY gonadal dysgenesis and the H-Y antigen. Report on 12 cases.

Authors:  U Wolf
Journal:  Hum Genet       Date:  1979-04-05       Impact factor: 4.132

2.  Response I to Gasser's letter.

Authors:  S Ohno
Journal:  Am J Hum Genet       Date:  1980-05       Impact factor: 11.025

Review 3.  Testis-organizing H-Y antigen as a discrete protein; its MHC restricted recognition and the genomic environment in which H-Y gene operates.

Authors:  S Ohno; J T Epplen; S Sutou
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

4.  Serology of H-Y antigen.

Authors:  G C Koo
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

5.  Sex-reversed XY females with campomelic dysplasia are H-Y negative.

Authors:  F D Bricarelli; M Fraccaro; J Lindsten; U Müller; P Baggio; L D Carbone; A Hjerpe; F Lindgren; A Mayerová; H Ringertz; E M Ritzén; D C Rovetta; C Sicchero; U Wolf
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

6.  Female phenotype and multiple abnormalities in sibs with a Y chromosome and partial X chromosome duplication: H--Y antigen and Xg blood group findings.

Authors:  R Bernstein; T Jenkins; B Dawson; J Wagner; G Dewald; G C Koo; S S Wachtel
Journal:  J Med Genet       Date:  1980-08       Impact factor: 6.318

Review 7.  Variability in serologically detected male antigen titer and some resulting problems: a critical review.

Authors:  M T Zenzes; T E Reed
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

8.  Application of monoclonal anti-HY antibody for human H-Y typing.

Authors:  G C Koo; N Tada; R Chaganti; U Hammerling
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

9.  Comments on some genetic abnormalities of sex determination and sex differentiation in Homo sapiens.

Authors:  J M Opitz
Journal:  Eur J Pediatr       Date:  1980-03       Impact factor: 3.183

10.  An XX male with a 46,XX/47,XX+Y(q12 to qter) karyotype.

Authors:  R Miró; M R Caballín; M D Coll; S Marina; J Egozcue
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

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