| Literature DB >> 6990205 |
M L Bekker, O K Kaboev, S V Koval'tsova.
Abstract
An UV-sensitive yeast mutant, uvs12, with almost unchanged sensitivity to gamma-irradiation and methylmethane sulphonate was obtained. uvs12, non allelic to any of the known UV-sensitive mutants from radI to rad21 is defective in early steps of excision repair. This inference is based on the fact that after 4-5 h post-irradiation incubation unexcised pyrimidine dimers are retained in nuclear DNA, which follows from two independent tests: the retention of UV-endonuclease-sensitive sites and enhanced survival after photoreactivation.Entities:
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Year: 1980 PMID： 6990205 DOI： 10.1007/BF00271495
Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925