| Literature DB >> 69878 |
D J Brock, L Barron, P Jelen, M Watt, J B Scrimgeour.
Abstract
In a prospective trial of 4224 pregnancies, 103 women had serum-alpha-fetoprotein (A.F.P.) above 2-3 times the median value for their stage of gestation. 10-7% of these delivered infants with birth-weights less than 2-5 kg. This was significantly greater than the rate of 4-2% for low-birth-weight infants in the general population. At higher multiples of the median serum-A.F.P. value the proportion of pregnancies leading to low-birth-weight infants was even greater. It is suggested that early identification of pregnancies with high risk of premature delivery may be an important corollary of maternal serum A.F.P. screening.Entities:
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Year: 1977 PMID： 69878 DOI： 10.1016/s0140-6736(77)90952-7
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321