Literature DB >> 6987403

Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.

D V Santi.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6987403     DOI： 10.1021/jm00176a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  10 in total

1.  DNA mismatch repair proficiency executing 5-fluorouracil cytotoxicity in colorectal cancer cells.

Authors:  Moriya Iwaizumi; Stephanie Tseng-Rogenski; John M Carethers
Journal:  Cancer Biol Ther       Date:  2011-10-15       Impact factor: 4.742

2.  The design of rational combination chemotherapy for cancer.

Authors:  E C Cadman
Journal:  West J Med       Date:  1984-06

3.  Antitumor cell and antimetabolic effects of 5-ethyl-2'-deoxyuridine and 5'-substituted 5-ethyl-2'-deoxyuridine derivatives.

Authors:  J Balzarini; E De Clercq; G Kiefer; K Keppeler; A Buchele
Journal:  Invest New Drugs       Date:  1984       Impact factor: 3.850

4.  Metabolism and mechanism of action of 5-fluorodeoxycytidine.

Authors:  E M Newman; D V Santi
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

Review 5.  DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.

Authors:  Long Shan Li; Julio C Morales; Martina Veigl; David Sedwick; Sheldon Greer; Mark Meyers; Mark Wagner; Richard Fishel; David A Boothman
Journal:  Br J Pharmacol       Date:  2009-09-23       Impact factor: 8.739

6.  Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.

Authors:  Moriya Iwaizumi; Stephanie Tseng-Rogenski; John M Carethers
Journal:  Mutat Res       Date:  2013-04-30       Impact factor: 2.433

7.  The role of fluorinated pyrimidine analogues in the induction of the in vitro expression of the fragile X chromosome.

Authors:  B Vandamme; I Liebaers; L Hens; J L Bernheim; C Roobol
Journal:  Hum Genet       Date:  1988-08       Impact factor: 4.132

8.  Trapping of 5-Fluorodeoxyuridine Monophosphate by Thymidylate Synthase Confers Resistance to 5-Fluorouracil.

Authors:  Chinatsu Kurasaka; Nana Nishizawa; Yoko Ogino; Akira Sato
Journal:  ACS Omega       Date:  2022-02-09

Review 9.  Mycoplasmas and cancer: focus on nucleoside metabolism.

Authors:  Johan Vande Voorde; Jan Balzarini; Sandra Liekens
Journal:  EXCLI J       Date:  2014-03-27       Impact factor: 4.068

10.  Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells.

Authors:  Chinatsu Kurasaka; Yoko Ogino; Akira Sato
Journal:  Int J Mol Sci       Date:  2021-03-13       Impact factor: 5.923
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.