Literature DB >> 6986267

Defective phagocytosis confined to Staphylococcus aureus in a female infant with recurrent infections.

S Ito, H Mikawa, T Hirao, T Yoshida, R Okuda.   

Abstract

Defective chemotaxis and phagocytosis of Staphylococcus aureus was identified in a female infant with marked hepatosplenomegaly and recurrent infections. Neutrophil mobilization from the marrow and marginal pool; random mobility; phagocytosis of yeast particles, latex beads and carbon particles; phagocytosis and intracellular killing capacity of Streptococcus pyogenes and E. coli; and NBT dye reduction were normal. Infiltration of neutrophils was depressed in the skin window test. The complement system and cellular immunity were intact. The patient also had a persistent EB virus infection. Defective phagocytosis limited to Staphylococcus aureus seems to be caused by an intrinsic cellular defect, such as congenital defect in neutrophil receptors for Staphylococcus aureus.

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Year:  1980        PMID： 6986267     DOI： 10.1007/BF00444748

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  27 in total

1.  Neutrophil actin dysfunction and abnormal neutrophil behavior.

Authors:  L A Boxer; E T Hedley-Whyte; T P Stossel
Journal:  N Engl J Med       Date:  1974-11-21       Impact factor: 91.245

2.  Familial short arm deletion of chromosome no. 15.

Authors:  J J Hoo; U Hillig; H Cramer; S Hansen; F Hermann
Journal:  Humangenetik       Date:  1974

3.  Phagocytosis in the newborn infant: humoral and cellular factors.

Authors:  M E Miller
Journal:  J Pediatr       Date:  1969-02       Impact factor: 4.406

4.  Defective neutrophil motility in children with measles.

Authors:  R Anderson; A R Rabson; R Sher; H J Koornhof
Journal:  J Pediatr       Date:  1976-07       Impact factor: 4.406

5.  Defective granulocyte chemotaxis in the Chediak-Higashi syndrome.

Authors:  R A Clark; H R Kimball
Journal:  J Clin Invest       Date:  1971-12       Impact factor: 14.808

6.  In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.

Authors:  P G Quie; J G White; B Holmes; R A Good
Journal:  J Clin Invest       Date:  1967-04       Impact factor: 14.808

7.  Interactions of the complement system with endotoxic lipopolysaccharide. Generation of a factor chemotactic for polymorphonuclear leukocytes.

Authors:  R Snyderman; H Gewurz; S E Mergenhagen
Journal:  J Exp Med       Date:  1968-08-01       Impact factor: 14.307

8.  Trypan blue inhibits complement-mediated phagocytosis by human polymorphonuclear leukocytes.

Authors:  J C Guckian; W D Christensen; D P Fine
Journal:  J Immunol       Date:  1978-05       Impact factor: 5.422

9.  Serum opsonin, bacteria, and polymorphonuclear leukocyte interactions in subacute bacterial endocarditis. Anti-gamma-globulin factors and their interaction with specific opsonins.

Authors:  R P Messner; T Laxidal; P G Quie; R C Williams
Journal:  J Clin Invest       Date:  1968-05       Impact factor: 14.808

10.  Studies on human leukocyte motility. I. Effects of alterations in pH, electrolyte concentration, and phagocytosis on leukocyte migration, adhesiveness, and aggregation.

Authors:  R E Bryant; R M DesPrez; M H VanWay; D E Rogers
Journal:  J Exp Med       Date:  1966-09-01       Impact factor: 14.307
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  2 in total

1.  Selective immunoglobulin M deficiency associated with disseminated molluscum contagiosum.

Authors:  M Mayumi; K Yamaoka; T Tsutsui; H Mizue; A Doi; M Matsuyama; S Ito; K Shinomiya; H Mikawa
Journal:  Eur J Pediatr       Date:  1986-04       Impact factor: 3.183

2.  DiGeorge syndrome with hypogammaglobulinaemia: a patient with excess suppressor T cell activity treated with fetal thymus transplantation.

Authors:  M Mayumi; H Kimata; Y Suehiro; S Hosoi; S Ito; Y Kuge; K Shinomiya; H Mikawa
Journal:  Eur J Pediatr       Date:  1989-04       Impact factor: 3.183
  2 in total

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