Literature DB >> 6984010

Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody.

F W Symington, B Subbarao, D E Mosier, J Sprent.   

Abstract

A DBA/1 B10.D2-specific monoclonal antibody (CY34) is described which defines a new murine B lymphocyte differentiation antigen designated Lyb-8.2. The ontogeny, strain distribution, and cell-surface density of the antigen were studied by radioimmunoassay and by fluorescence-activated cell sorter (FACS) analysis. Lyb-8.2 appears to be expressed on pre-B cells and on all mature B lymphocytes. Lyb-8.2 molecules immunoprecipitated from surface labeled B10.D2 spleen cells migrated in polyacrylamide gels with an apparent mol. wt. of 95,000-105,000 daltons and were bound by lentil lectin. The expression of Lyb-8.2 is controlled by a locus on chromosome 7 that is closely linked to Gpi-1 and RP-2. Added Lyb-8.2-specific antibody did not measurably impair B lymphocyte function in several in vitro systems studied.

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Year:  1982        PMID： 6984010     DOI： 10.1007/BF00372098

Source DB:  PubMed          Journal:  Immunogenetics        ISSN： 0093-7711            Impact factor:   2.846


  30 in total

1.  Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose.

Authors:  P L Ey; S J Prowse; C R Jenkin
Journal:  Immunochemistry       Date:  1978-07

2.  Selective suppression of reactivity to rat histocompatibility antigens by hybridoma antibodies.

Authors:  T J McKearn; M Sarmiento; A Weiss; F P Stuart; F W Fitch
Journal:  Curr Top Microbiol Immunol       Date:  1978       Impact factor: 4.291

3.  Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3alpha,6alpha-diphenylglycoluril.

Authors:  M A Markwell; C F Fox
Journal:  Biochemistry       Date:  1978-10-31       Impact factor: 3.162

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Establishment and characterization of BALB/c lymphoma lines with B cell properties.

Authors:  K J Kim; C Kanellopoulos-Langevin; R M Merwin; D H Sachs; R Asofsky
Journal:  J Immunol       Date:  1979-02       Impact factor: 5.422

6.  A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion.

Authors:  F W Symington; J Sprent
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

7.  Fractionation of lymphocyte populations with monoclonal antibodies specific for LYT-2.2 and LYT-3.1.

Authors:  D H Raulet; P D Gottlieb; M J Bevan
Journal:  J Immunol       Date:  1980-09       Impact factor: 5.422

8.  A new mouse cell-surface antigen (Ly-m18) defined by a monoclonal antibody.

Authors:  S Kimura; N Tada; Y Liu; U Hämmerling
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

9.  A new mouse cell-surface antigen (Ly-m20) controlled by a gene linked to Mls locus and defined by monoclonal antibodies.

Authors:  S Kimura; N Tada; E Nakayama; Y Liu; U Hämmerling
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846

10.  DNL 1.9: a monoclonal antibody which specifically detects all murine B lineage cells.

Authors:  D S Dessner; M R Loken
Journal:  Eur J Immunol       Date:  1981-04       Impact factor: 5.532
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  10 in total

Review 1.  Mouse chromosome 7.

Authors:  E M Rinchik; T Magnuson; B Holdener-Kenny; G Kelsey; A Bianchi; C J Conti; F Chartier; K A Brown; S D Brown; J Peters
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Improvement of amphotericin B activity during experimental cryptococcosis by incorporation into specific immunoliposomes.

Authors:  F Dromer; J Barbet; J Bolard; J Charreire; P Yeni
Journal:  Antimicrob Agents Chemother       Date:  1990-11       Impact factor: 5.191

Review 3.  Mouse map of paralogous genes.

Authors:  J H Nadeau; M Kosowsky
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Ly-39: a new lymphocyte alloantigen defined with a monoclonal antibody.

Authors:  E Park; M A Principato; M C Lamers; H B Dickler
Journal:  Immunogenetics       Date:  1988       Impact factor: 2.846

5.  Genetic nomenclature for loci controlling mouse lymphocyte antigens.

Authors:  H C Morse; F W Shen; U Hämmerling
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

6.  The alpha/beta sheath and its cytoplasmic tyrosines are required for signaling by the B-cell antigen receptor but not for capping or for serine/threonine-kinase recruitment.

Authors:  G T Williams; C J Peaker; K J Patel; M S Neuberger
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

7.  Differential expression of CD22 (Lyb8) on murine B cells.

Authors:  L D Erickson; L T Tygrett; S K Bhatia; K H Grabstein; T J Waldschmidt
Journal:  Int Immunol       Date:  1996-07       Impact factor: 4.823

8.  B cell depletion reduces the number of autoreactive T helper cells and prevents glucose-6-phosphate isomerase-induced arthritis.

Authors:  Oliver Frey; Lisa Bruns; Lars Morawietz; Kyri Dunussi-Joannopoulos; Thomas Kamradt
Journal:  PLoS One       Date:  2011-09-08       Impact factor: 3.240

9.  Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes.

Authors:  K L Holmes; J H Pierce; W F Davidson; H C Morse
Journal:  J Exp Med       Date:  1986-08-01       Impact factor: 14.307

10.  Expression of murine Lm-1 locus. Lm-1 determinants on lymphocytes and macrophages, and effects of Lm-1 incompatibility on bone marrow grafts.

Authors:  M M O'Toole; G C Bosma; M J Bosma
Journal:  J Exp Med       Date:  1985-08-01       Impact factor: 14.307
  10 in total

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