Literature DB >> 6983693

Leukemia-derived growth factor (non-interleukin 2) produced by a human malignant T lymphoid cell line.

C H Uittenbogaart, J L Fahey.   

Abstract

A growth factor was found in the supernatants of MOLT-4f, a cell line derived from acute T lymphoblastic leukemia. This factor, which we designated leukemia-derived growth factor from MOLT-4f (LDGF-M4), is different from interleukin 2. LDGF-M4 has features of a polypeptide with a molecular weight in the range of 5,000-15,000, as indicated by gel diffusion chromatography. LDGF-M4 does stimulate MOLT-4f and at least two other T cell lines that do not respond to interleukin 2. Because MOLT-4f cells produce and respond to LDGF-M4, this factor may contribute to the independence of MOLT-4f and related T leukemia cell lines.

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Year:  1982        PMID： 6983693      PMCID： PMC347263          DOI： 10.1073/pnas.79.22.7004

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  13 in total

1.  Functional and morphologic characterization of human T cells continuously grown in vitro.

Authors:  F W Ruscetti; D A Morgan; R C Gallo
Journal:  J Immunol       Date:  1977-07       Impact factor: 5.422

2.  Selective in vitro growth of T lymphocytes from normal human bone marrows.

Authors:  D A Morgan; F W Ruscetti; R Gallo
Journal:  Science       Date:  1976-09-10       Impact factor: 47.728

3.  Growth factors from murine sarcoma virus-transformed cells.

Authors:  J E de Larco; G J Todaro
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

4.  Studies on carcinogenesis by avian sarcoma viruses. 3. The differential effect of serum and polyanions on multiplication of uninfected and converted cells.

Authors:  H M Temin
Journal:  J Natl Cancer Inst       Date:  1966-08       Impact factor: 13.506

5.  T cell growth factor: parameters of production and a quantitative microassay for activity.

Authors:  S Gillis; M M Ferm; W Ou; K A Smith
Journal:  J Immunol       Date:  1978-06       Impact factor: 5.422

Review 6.  Growth factors in mammalian cell culture.

Authors:  D Gospodarowicz; J S Moran
Journal:  Annu Rev Biochem       Date:  1976       Impact factor: 23.643

7.  Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

Authors:  G J Todaro; C Fryling; J E De Larco
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

8.  Continued growth of functional human T lymphocytes: production of human T-cell growth factor.

Authors:  G D Bonnard; K Yasaka; R D Maca
Journal:  Cell Immunol       Date:  1980-05       Impact factor: 4.868

9.  Complete replacement of serum by albumin, transferrin, and soybean lipid in cultures of lipopolysaccharide-reactive B lymphocytes.

Authors:  N N Iscove; F Melchers
Journal:  J Exp Med       Date:  1978-03-01       Impact factor: 14.307

10.  Production of macrophage migration inhibition factor by continuous cell lines.

Authors:  D G Tubergen; J D Feldman; E M Pollock; R A Lerner
Journal:  J Exp Med       Date:  1972-02-01       Impact factor: 14.307
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  5 in total

1.  The effects of interleukins and other soluble factors on T-lymphocyte colony formation.

Authors:  A Winkelstein; P L Simon; D Wood; L L Machen; R K Shadduck; A Waheed
Journal:  Immunology       Date:  1986-06       Impact factor: 7.397

2.  N-terminal amino acid sequence of leukemia derived growth factor (LGF) from human erythroleukemia cell culture.

Authors:  A Mihara; K Fujiwara; S Sato; T Okabe; N Fujiyoshi
Journal:  In Vitro Cell Dev Biol       Date:  1987-04

3.  The marmoset B-lymphoblastoid cell line (B95-8) produces and responds to B-cell growth and differentiation factors: role of shed CD23 (sCD23).

Authors:  R E Callard; Y L Lau; J G Shields; S H Smith; J Cairns; L Flores-Romo; J Gordon
Journal:  Immunology       Date:  1988-11       Impact factor: 7.397

4.  Leukemia-derived growth factor (non-interleukin-2) produced by murine lymphoma T-cell lines.

Authors:  E F Hays; D Goodrum; M Bessho; S Kitada; C H Uittenbogaart
Journal:  Proc Natl Acad Sci U S A       Date:  1984-12       Impact factor: 11.205

5.  Soluble factor requirements for the autostimulatory growth of B lymphoblasts immortalized by Epstein-Barr virus.

Authors:  J Gordon; S C Ley; M D Melamed; P Aman; N C Hughes-Jones
Journal:  J Exp Med       Date:  1984-05-01       Impact factor: 14.307
  5 in total

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