Display and analysis of cell size distributions with a Coulter Counter interfaced to an Apple II microcomputer.

A model ZBI Coulter Counter was interfaced to an Apple II microcomputer via analog and digital interfaces. It was possible to obtain a graphic display of cell size versus channel number (1000 channels), integration of selected channels, plots, listings, and storage of the data on floppy disk, using a convenient menu selection enabling operators unfamiliar with computer technology to master the system quickly. Examples are presented of calibration of the Coulter Counter and its use for rapid and precise analysis of E rosettes.