Literature DB >> 6982139

Functional alterations in non-T cells in rheumatic heart disease.

E D Gray, W E Regelmann, L W Wannamaker, A El Kholy, Z H Abdin.   

Abstract

The mediation of the T cell lymphoproliferative response to streptococcal blastogen A by non-T mononuclear cells was studied in patients with rheumatic heart disease (RHD) and control subjects. Non-T cells are essential for T cell response to blastogen A. Non-T cells from RHD patients were less effective in enabling the T lymphocyte response to blastogen A than control non-T cells though no consistent difference was observed in the response to phytohaemagglutinin. The results suggest that a functional alteration is present in the non-T cells from RHD patients which might be related to the pathogenesis of the disease.

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Year:  1982        PMID： 6982139      PMCID： PMC1536509     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  10 in total

1.  Discrepancy between PHA responsiveness and quantitative estimates of T-cell numbers in human peripheral blood during chronic renal failure and immunosuppression after transplantation.

Authors:  C Lopez; R L Simmons; J L Touraine; B H Park; D F Kiszkiss; J S Najarian; R A Good
Journal:  Clin Immunol Immunopathol       Date:  1975-05

2.  THE ACTION OF STREPTOLYSIN S ON PERIPHERAL LYMPHOCYTES OF NORMAL SUBJECTS AND PATIENTS WITH ACUTE RHEUMATIC FEVER.

Authors:  K HIRSCHHORN; R R SCHREIBMAN; S VERBO; R H GRUSKIN
Journal:  Proc Natl Acad Sci U S A       Date:  1964-11       Impact factor: 11.205

3.  Lymphocyte transformation with streptolysin S preparations and inhibition of streptolysin S by serum in rheumatic fever and other rheumatic diseases.

Authors:  G Cuppari; F Quagliata; A Ieri; A Taranta
Journal:  J Lab Clin Med       Date:  1972-08

4.  Impaired lymphocyte stimulation by some streptococcal antigens in patients with recurrent aphthous stomatitis and rheumatic heart disease.

Authors:  T C Francis; J J Oppenheim
Journal:  Clin Exp Immunol       Date:  1970-04       Impact factor: 4.330

5.  Association of a B-cell alloantigen with susceptibility to rheumatic fever.

Authors:  M E Patarroyo; R J Winchester; A Vejerano; A Gibofsky; F Chalem; J B Zabriskie; H G Kunkel
Journal:  Nature       Date:  1979-03-08       Impact factor: 49.962

6.  Immunogenetics of response to a purified antigen from group A streptococci. II. Linkage of response to HLA.

Authors:  L J Greenberg; R L Chopyk; P W Bradley; J M Lalouel
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

7.  Immunogenetics of response to a purified antigen from group A streptococci. I. Complex segregation analysis.

Authors:  L J Greenberg; P W Bradley; R L Chopyk; J M Lalouel
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

Review 8.  Selective triggering of human T and B lymphocytes in vitro by polyclonal mitogens.

Authors:  M Greaves; G Janossy; M Doenhoff
Journal:  J Exp Med       Date:  1974-07-01       Impact factor: 14.307

9.  Purification and properties of an extracellular blastogen produced by group A streptococci.

Authors:  E D Gray
Journal:  J Exp Med       Date:  1979-06-01       Impact factor: 14.307

10.  Cellular interactions in the proliferative response of human T and B lymphocytes to phytomitogens and allogeneic lymphocytes.

Authors:  H P Lohrmann; L Novikovs; R G Graw
Journal:  J Exp Med       Date:  1974-06-01       Impact factor: 14.307
  10 in total
  1 in total

1.  Serial studies on the cellular immune response to streptococcal antigens in acute and convalescent rheumatic fever patients in Trinidad.

Authors:  S E Read; H F Reid; V A Fischetti; T Poon-King; R Ramkissoon; M McDowell; J B Zabriskie
Journal:  J Clin Immunol       Date:  1986-11       Impact factor: 8.317
  1 in total

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