Literature DB >> 6981387

Association of HLA-Aw31 and HLA-DR1 with adult rheumatoid arthritis.

B Schiff, Y Mizrachi, S Orgad, M Yaron, E Gazit.   

Abstract

Forty-nine Israeli Jewish patients with rheumatoid arthritis (RA) were studied for their HLA A, B, C, DR antigen frequency. A significant increase in HLA Aw31 and HLA DR1 was observed (p less than 5.10(-5) and p less than 5.10(-3) respectively). 45% of Aw31 positive patients were sero-negative for rheumatoid factor, while most HLA DR1 positive individuals were seropositive. DR5 was found to be significantly decreased (p less than 5.10(-4)). Contrary to previous reports, DRw4 was found to be within the range of antigen frequency of the controls (34.7% vs. 32%). It is suggested that in our population of patients Aw31 and DR1 and not DR4 are highly associated with adult onset of RA.

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Year:  1982        PMID： 6981387      PMCID： PMC1000958          DOI： 10.1136/ard.41.4.403

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  9 in total

1.  The association of HL-A-B8 and childhood celiac disease in an Israeli population.

Authors:  E Gazit; S Avigad; Z Zfat; T Efter; Y Mizrachi; Y Rotem
Journal:  Isr J Med Sci       Date:  1977-04

2.  HL-A, immune-response genes, and disease.

Authors:  H O McDevitt; W F Bodmer
Journal:  Lancet       Date:  1974-06-22       Impact factor: 79.321

3.  HLA-DRw4 and rheumatoid arthritis.

Authors:  G Husby; J T Gran; M Ostensen; A Johannessen; E Thorsby
Journal:  Lancet       Date:  1979-03-10       Impact factor: 79.321

4.  HLA-D and DR determinants in rheumatoid arthritis.

Authors:  D Jaraquemada; C Pachoula-Papasteriadis; H Festenstein; J A Sachs; I M Roitt; M Corbett; B Ansell
Journal:  Transplant Proc       Date:  1979-06       Impact factor: 1.066

5.  Simultaneous detection of two cell populations by two-colour fluorescence and application to the recognition of B-cell determinants.

Authors:  J J van Rood; A van Leeuwen; J S Ploem
Journal:  Nature       Date:  1976-08-26       Impact factor: 49.962

6.  Mixed lymphocyte cultures in rheumatoid arthritis.

Authors:  P Stastny
Journal:  J Clin Invest       Date:  1976-05       Impact factor: 14.808

Review 7.  Familial rheumatoid arthritis: linkage of HLA to disease susceptibility locus in four families where proband presented with juvenile rheumatoid arthritis.

Authors:  R D Rossen; E J Brewer; R M Sharp; J Ott; J W Templeton
Journal:  J Clin Invest       Date:  1980-03       Impact factor: 14.808

8.  Association of the B-cell alloantigen DRw4 with rheumatoid arthritis.

Authors:  P Stastny
Journal:  N Engl J Med       Date:  1978-04-20       Impact factor: 91.245

9.  HLA antigen in Jewish patients with juvenile diabetes mellitus.

Authors:  E Gazit; A Sartani; Y Mizrachi; M Ravid
Journal:  Diabete Metab       Date:  1977-03
  9 in total
  38 in total

Review 1.  The immunogenetics of rheumatoid arthritis.

Authors:  B P Wordsworth; J I Bell
Journal:  Springer Semin Immunopathol       Date:  1992

Review 2.  Polygenic susceptibility in rheumatoid arthritis.

Authors:  P Wordsworth; J Bell
Journal:  Ann Rheum Dis       Date:  1991-06       Impact factor: 19.103

3.  Detecting disease-predisposing variants: the haplotype method.

Authors:  A M Valdes; G Thomson
Journal:  Am J Hum Genet       Date:  1997-03       Impact factor: 11.025

4.  HLA-DR4-DQw8, but not DR4-DQw7 haplotypes occur in Indian patients with rheumatoid arthritis.

Authors:  V Taneja; N K Mehra; A N Chandershekaran; R K Ahuja; Y N Singh; A N Malaviya
Journal:  Rheumatol Int       Date:  1992       Impact factor: 2.631

5.  Immunogenetic markers in rheumatic diseases.

Authors:  L Martin; M J Fritzler
Journal:  Can Fam Physician       Date:  1990-03       Impact factor: 3.275

Review 6.  T cell receptor genes in rheumatoid arthritis.

Authors:  J P Dutz; A Chan; T Mak; K A Siminovitch; L A Rubin
Journal:  Springer Semin Immunopathol       Date:  1989

7.  Current imaging strategies in rheumatoid arthritis.

Authors:  Merissa N Zeman; Peter Jh Scott
Journal:  Am J Nucl Med Mol Imaging       Date:  2012-03-28

8.  Association of HLA-B35 with mucocutaneous lesions in Israeli patients with rheumatoid arthritis receiving gold treatment.

Authors:  M Tishler; D Caspi; E Gazit; M Yaron
Journal:  Ann Rheum Dis       Date:  1988-03       Impact factor: 19.103

9.  HLA haplotype sharing by siblings with rheumatoid arthritis: evidence for genetic heterogeneity.

Authors:  D M Grennan; P A Sanders; P A Dyer; R Harris
Journal:  Ann Rheum Dis       Date:  1986-02       Impact factor: 19.103

10.  Weak association between HLA-DR4 and rheumatoid arthritis in Chilean patients.

Authors:  L Massardo; S Jacobelli; L Rodríguez; S Rivero; A González; R Marchetti
Journal:  Ann Rheum Dis       Date:  1990-05       Impact factor: 19.103
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