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Literature DB >> 6980675

Pharmacological dissection of charge movement in frog skeletal muscle fibers.

Abstract

When charge movement is measured from muscle fibers bathed in a moderately hypertonic solution, a secondary hump appears in the decay phase of the signal during the "on" of the test pulse. The hump can be suppressed by the application of dantrolene sodium or tetracaine. The amount of charge associated with the hump is approximately 20-25% of the total charge. All the observed properties of the hump charge are consistent with the possibility that it is more closely associated with calcium release from the sarcoplasmic reticulum, and thus more relevant to excitation-contraction coupling, than the rest of the charge.

Entities: Chemical Disease

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Year: 1982 PMID： 6980675 PMCID： PMC1328918 DOI： 10.1016/S0006-3495(82)84498-6

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

18 in total

Pharmacological dissection of charge movement in frog skeletal muscle fibers.

1. Charge movement and mechanical repriming in skeletal muscle.

2. A non-linear voltage dependent charge movement in frog skeletal muscle.

3. Some dielectric properties of muscle membrane and their possible importance for excitation-contraction coupling.

4. A gating signal for the potassium channel?

5. Charge movement and membrane capacity in frog muscle.

6. Arsenazo III signals in singly dissected frog twitch fibres [proceedings].

7. Effects of tetracaine on displacement currents and contraction of frog skeletal muscle.

8. Effects of glycerol treatment and maintained depolarization on charge movement in skeletal muscle.

9. Differential effects of tetracaine on delayed potassium channels and displacement currents in frog skeletal muscle.

10. Calcium transients in amphibian muscle.

1. Existence of Q gamma in frog cut twitch fibers with little Q beta.

2. Association of the Igamma and Idelta charge movement with calcium release in frog skeletal muscle.

3. Differential effects of tetracaine on two kinetic components of calcium release in frog skeletal muscle fibres.

4. Differential suppression of charge movement components by gluconate in cut twitch fibres of Rana temporaria.

5. The effect of phenylglyoxal on contraction and intramembrane charge movement in frog skeletal muscle.

6. Suppression of charge movement in frog skeletal muscle by D600.

7. Time domain spectroscopy of the membrane capacitance in frog skeletal muscle.

8. Effects of tetracaine on charge movements and calcium signals in frog skeletal muscle fibers.

9. Charge movement in a fast twitch skeletal muscle from rat.

10. Paralysis of frog skeletal muscle fibres by the calcium antagonist D-600.