Literature DB >> 6980663

Cell lines derived from a human myelomonocytic leukaemia.

T R Bradley, G Pilkington, M Garson, G S Hodgson, N Kraft.   

Abstract

Two cell lines have been isolated from separate samples, taken at the same time, from the peripheral blood of a case of myelomonocytic leukaemia. One of these (CESS-B) is a typical B cell line obtained after treatment of the peripheral blood white cells with Epstein-Barr virus (EBV). The second line (RC-2) is a monocyte-macrophage type, originally isolated by 5 months continuous culture in the presence of colony stimulating factor (CSF). Subsequently, after further culture, this line has become autonomous (RC-2A), no longer requiring CSF for maintenance of proliferation, whilst retaining the characteristics of the original line.

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Year:  1982        PMID： 6980663     DOI： 10.1111/j.1365-2141.1982.tb02823.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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