Literature DB >> 6980542

Alpha1-antitrypsin: evidence for a fourth PiM allele. Distribution of the PiM subtypes in Southern Germany.

S Weidinger, H Cleve, W Patutschnick.   

Abstract

Subtypes of the protease inhibitor (Pi) alpha 1-antitrypsin were determined in sera from 752 unrelated individuals from Southern Germany. By isoelectric focusing nine common PiM subtypes were distinguished and several rare Pi variants were observed. Family studies confirm the existence of a fourth PiM suballele. The frequency of PiM4 was found to be 0.018. A survey of the distribution of Pi alleles is given; the application of Pi subtyping in cases of disputed paternity is discussed.

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Year:  1982        PMID： 6980542     DOI： 10.1007/BF00200725

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN： 0044-3433


  14 in total

1.  Alpha1-antitrypsin: further genetic heterogeneity revealed by isoelectric focusing.

Authors:  F Kueppers; M J Christopherson
Journal:  Am J Hum Genet       Date:  1978-07       Impact factor: 11.025

2.  1 -Antitrypsin deficiency: a variant with no detectable 1 -antitrypsin.

Authors:  R C Talamo; C E Langley; C E Reed; S Makino
Journal:  Science       Date:  1973-07-06       Impact factor: 47.728

3.  Serum prealbumin: polymorphism in man.

Authors:  M K Fagerhol; M Braend
Journal:  Science       Date:  1965-08-27       Impact factor: 47.728

4.  Report of Nomenclature Meeting for alpha 1-antitrypsin, INSERM, Rouen/Bois-Guillaume-1978.

Authors:  D W Cox; A M Johnson; M K Fagerhol
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

5.  Reliable classification of six Pi M subtypes by separator isoelectric focusing.

Authors:  R R Frants; A W Eriksson
Journal:  Hum Hered       Date:  1978       Impact factor: 0.444

6.  Phenotype and gene distribution of alpha-1-antitrypsin in a North Italian population.

Authors:  E C Klasen; F D'Andrea; L F Bernini
Journal:  Hum Hered       Date:  1978       Impact factor: 0.444

7.  Population genetics of alpha1-antitrypsin in the Netherlands. Description of a new electrophoretic variant.

Authors:  E C Klasen; C Franken; W S Volkers; L F Bernini
Journal:  Hum Genet       Date:  1977-07-26       Impact factor: 4.132

8.  Genetic variations of serum alpha-1-antitrypsin (Pi types) in Normans. Common Pi M subtypes and new phenotypes.

Authors:  R Charlionet; R Sesboüe; C Morcamp; F Lefebvre; J P Martin
Journal:  Hum Hered       Date:  1981       Impact factor: 0.444

9.  Pi M4: an additional Pi M subtype.

Authors:  J Constans; M Viau; C Gouaillard
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

10.  Pi subtyping by isoelectric focusing: further genetic studies and application to paternity examinations.

Authors:  S Weidinger; F Schwarzfischer; H Cleve
Journal:  Z Rechtsmed       Date:  1980
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  7 in total

1.  Does the PI polymorphism alone control alpha-1-antitrypsin expression?

Authors:  N G Martin; P Clark; A F Ofulue; L J Eaves; L A Corey; W E Nance
Journal:  Am J Hum Genet       Date:  1987-03       Impact factor: 11.025

2.  Improved resolution of PI (alpha 1-antitrypsin) phenotypes by a large-scale immobilized pH gradient.

Authors:  A Görg; W Postel; J Weser; W Patutschnick; H Cleve
Journal:  Am J Hum Genet       Date:  1985-09       Impact factor: 11.025

3.  Distribution of the Pi, TfC, and Gc subtypes in Galicia (North West Spain).

Authors:  A Carracedo; L Concheiro
Journal:  Z Rechtsmed       Date:  1983

4.  PI(alpha 1-antitrypsin) polymorphism in the Japanese: confirmation of PI*M4 and description of new PI variants.

Authors:  I Yuasa; K Suenaga; Y Gotoh; K Ito; N Yokoyama; K Okada
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

5.  alpha 1-Antitrypsin (Pi) types and subtypes in the Tyrolean population.

Authors:  A Böhme; H Cleve; D Schönitzer; H Reissigl; S Kazda; W Müller
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

6.  Alpha-1-antitrypsin: evidence for a fifth PI M subtype and a new deficiency allele PI*Z augsburg.

Authors:  S Weidinger; W Jahn; F Cujnik; F Schwarzfischer
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

7.  Geographical variability of alpha-1-antitrypsin alleles in China: a study on six Chinese populations.

Authors:  Q L Ying; M L Zhang; C C Liang; X P Liu; Y W Huang; R X Wang; N J Zhang; L C Chen; L F Chen; N C Yu
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132
  7 in total

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