| Literature DB >> 697951 |
E Keystone, D Taylor-Robinson, C Pope, G Taylor, P Furr.
Abstract
Mycoplasma pulmonis inoculated parenterally into mice deficient in the fifth component of complement (C5) caused a chronic arthritis of significantly greater magnitude than in immunologically normal mice. During the chronic phase of arthritis M pulmonis organisms were isolated from the joints and organs of C5 deficient mice more frequently and in larger numbers than from immunologically normal mice. The implications of the results are discussed in relation to the pathogenesis of M pulmonis induced arthritis and human connective tissue diseases.Entities:
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Year: 1978 PMID： 697951 DOI： 10.1002/art.1780210709
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591