Literature DB >> 6978886

Simultaneous measurement of 5-hydroxytryptophan and L-dihydroxyphenylalanine by high-performance liquid chromatography with electrochemical detection. Measurement of serotonin and catecholamine turnover in discrete brain regions.

A Shum, M J Sole, G R Van Loon.   

Abstract

A sensitive method, using reversed-phase high-performance liquid chromatography with electrochemical detection, which allows the measurement of both 5-hydroxytryptophan and L-dihydroxyphenylalanine is described. This method, used in conjunction with the administration in vivo of an L-aromatic amino acid decarboxylase inhibitor, allows the simultaneous measurement of serotonin and catecholamine synthesis rates in small discrete brain regions.

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Year:  1982        PMID： 6978886     DOI： 10.1016/s0378-4347(00)80425-9

Source DB:  PubMed          Journal:  J Chromatogr


  12 in total

1.  (+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors.

Authors:  K Svensson; S Hjorth; D Clark; A Carlsson; H Wikström; B Andersson; D Sanchez; A M Johansson; L E Arvidsson; U Hacksell
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

2.  Rat brain concentration of administered amino acids: dependence on time of day for administration.

Authors:  T Eriksson; K Wiesel; A Carlsson
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

3.  The 5-HT 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo.

Authors:  S Hjorth; T Magnusson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-11       Impact factor: 3.000

4.  Effects of the partial dopamine receptor agonists SDZ 208-911, SDZ 208-912 and terguride on central monoamine receptors. A behavioral, biochemical and electrophysiological study.

Authors:  K Svensson; A Ekman; M F Piercey; W E Hoffmann; J T Lum; A Carlsson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-09       Impact factor: 3.000

5.  Effects of capsaicin on central monoaminergic mechanisms in the rat.

Authors:  M Hajós; K Svensson; H Nissbrandt; F Obál; A Carlsson
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

6.  Central dopaminergic properties of HW-165 and its enantiomers; trans-octahydrobenzo(f)quinoline congeners of 3-PPP.

Authors:  S Hjorth; K Svensson; A Carlsson; H Wikström; B Andersson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-07       Impact factor: 3.000

7.  Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.

Authors:  S Hjorth; A Carlsson; D Clark; K Svensson; H Wikström; D Sanchez; P Lindberg; U Hacksell; L E Arvidsson; A Johansson
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

8.  (+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists.

Authors:  K Svensson; A M Johansson; T Magnusson; A Carlsson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-11       Impact factor: 3.000

9.  Development of dopamine autoreceptors in the postnatal rat brain.

Authors:  T Hedner; P Lundborg
Journal:  J Neural Transm       Date:  1985       Impact factor: 3.575

10.  GBR 13098, a selective dopamine uptake inhibitor; behavioural, biochemical and electrophysiological studies.

Authors:  E Pileblad; G Engberg
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-12       Impact factor: 3.000
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