Literature DB >> 6978472

Modulation of voltage-dependent currents by muscarinic receptor in sympathetic neurones of bullfrog.

T Akasu, K Koketsu.   

Abstract

The muscarinic actions of acetylcholine (ACh) on the action potentials of bullfrog sympathetic ganglion cells were studied with voltage-clamp experiments. The slow inward current (Isi) carried by Ca2+ was markedly depressed by ACh. ACh also markedly depressed the time-dependent outward current following Isi. The outward current was composed of two components, a TEA-sensitive rectifier K+ current (IK1) and a TEA-insensitive slow rectifier K+ current (IK2). Both of these components were depressed by ACh.

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Year:  1982        PMID: 6978472     DOI: 10.1016/0304-3940(82)90361-5

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  8 in total

1.  Identification of delayed potassium and calcium currents in the rat sympathetic neurone under voltage clamp.

Authors:  O Belluzzi; O Sacchi; E Wanke
Journal:  J Physiol       Date:  1985-01       Impact factor: 5.182

2.  The Ca2+-sensitive K+-currents underlying the slow afterhyperpolarization of bullfrog sympathetic neurones.

Authors:  K Tanaka; K Kuba
Journal:  Pflugers Arch       Date:  1987-10       Impact factor: 3.657

3.  Two components of muscarine-sensitive membrane current in rat sympathetic neurones.

Authors:  D A Brown; A A Selyanko
Journal:  J Physiol       Date:  1985-01       Impact factor: 5.182

4.  Acetylcholine raises excitability by inhibiting the fast transient potassium current in cultured hippocampal neurons.

Authors:  Y Nakajima; S Nakajima; R J Leonard; K Yamaguchi
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

5.  Muscarinic modulation of calcium dependent plateau potentials in rat neostriatal neurons.

Authors:  U Misgeld; P Calabresi; H U Dodt
Journal:  Pflugers Arch       Date:  1986-11       Impact factor: 3.657

6.  Muscarinic and peptidergic excitation of bull-frog sympathetic neurones.

Authors:  S W Jones
Journal:  J Physiol       Date:  1985-09       Impact factor: 5.182

7.  The effects of soman on the electrical properties and excitability of bullfrog sympathetic ganglion neurones.

Authors:  T J Heppner; J F Fiekers
Journal:  Br J Pharmacol       Date:  1991-08       Impact factor: 8.739

8.  Effects of oxotremorine and RMI 12330 A on [3H]acetylcholine release and adenylate cyclase activity in guinea pig superior cervical ganglion.

Authors:  A Capuzzo; P G Borasio; E Fabbri
Journal:  Neurochem Res       Date:  1988-11       Impact factor: 3.996

  8 in total

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