Literature DB >> 6977400

Epidermal growth factor in the healing of second degree burns: a controlled animal study.

J W Thornton, C A Hess, V Cassingham, R H Bartlett.   

Abstract

The effects of the topical application of epidermal growth factor (EGF) on the healing of partial-thickness scald burns in rats was evaluated. Time to complete healing, the rate of healing, daily percentage weight change, and cell growth were the measured parameters. We were able to demonstrate an insignificant healing advantage with the topical application of EGF, by itself or in combination with silver sulphadiazine. This insignificant healing advantage does not warrant clinical evaluation.

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Year:  1982        PMID: 6977400     DOI: 10.1016/0305-4179(82)90079-1

Source DB:  PubMed          Journal:  Burns Incl Therm Inj


  6 in total

1.  Improvement in wound healing by epidermal growth factor (EGF) ointment. I. Effect of nafamostat, gabexate, or gelatin on stabilization and efficacy of EGF.

Authors:  K Okumura; Y Kiyohara; F Komada; S Iwakawa; M Hirai; T Fuwa
Journal:  Pharm Res       Date:  1990-12       Impact factor: 4.200

2.  Topical treatment of standardised burns with herbal remedies in model rats.

Authors:  Fahir Becić; Nedzad Mulabegović; Zakira Mornjaković; Elvedina Kapić; Senad Prasović; Ervina Becić; Jasna Kusturica
Journal:  Bosn J Basic Med Sci       Date:  2005-11       Impact factor: 3.363

3.  Acceleration of tensile strength of incisions treated with EGF and TGF-beta.

Authors:  G L Brown; L J Curtsinger; M White; R O Mitchell; J Pietsch; R Nordquist; A von Fraunhofer; G S Schultz
Journal:  Ann Surg       Date:  1988-12       Impact factor: 12.969

4.  Evaluation of the release rate of bioactive recombinant human epidermal growth factor from crosslinking collagen sponges.

Authors:  Chih-Hui Yang
Journal:  J Mater Sci Mater Med       Date:  2007-10-04       Impact factor: 3.896

5.  Epidermal growth factor-containing wound closure enhances wound healing in non-diabetic and diabetic rats.

Authors:  S Dogan; S Demirer; I Kepenekci; B Erkek; A Kiziltay; N Hasirci; S Müftüoglu; A Nazikoglu; N Renda; U D Dincer; A Elhan; E Kuterdem
Journal:  Int Wound J       Date:  2009-04       Impact factor: 3.315

6.  Enhancement of epidermal regeneration by biosynthetic epidermal growth factor.

Authors:  G L Brown; L Curtsinger; J R Brightwell; D M Ackerman; G R Tobin; H C Polk; C George-Nascimento; P Valenzuela; G S Schultz
Journal:  J Exp Med       Date:  1986-05-01       Impact factor: 14.307

  6 in total

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