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Literature DB >> 6977392

Comparison of currently available monoclonal antibodies with conventional markers for phenotyping of one hundred acute leukemias.

E Thiel, U Kummer, H Rodt, K Stünkel, R Munker, O Majdic, W Knapp, S Thierfelder.

Abstract

One hundred acute leukemia cell samples (89 ALL, 11 AMML) derived from children's bone marrow at diagnosis were typed for the reaction with 15 monoclonal antibodies (mAbs). Subdivision in ALL-subgroups was performed according to conventional markers. Only some mAbs like VIL-Al which is directed against the cALL-antigen, can substitute polyclonal rabbit antisera. Additional subclassifications became evident by the use of mAbs for T-cell differentiated ALL forms. However, unexpected negative reactions must be taken into account as observed for all T-directed mAbs with individual T-cell ALL samples.

Entities: Disease Gene Species

Mesh：

Substances：
Antibodies, Monoclonal

Year: 1982 PMID： 6977392 DOI： 10.1007/BF00320096

Source DB: PubMed Journal: Blut ISSN： 0006-5242

12 in total

Review 1. [Leukemic cell phenotypes and the lymphoid differentiation pathway (author's transl)].

Authors: E Thiel; H Rodt; S Thierfelder
Journal: Haematologica Date: 1981-08 Impact factor: 9.941

2. Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody.

Authors: P C Beverley; R E Callard
Journal: Eur J Immunol Date: 1981-04 Impact factor: 5.532

3. Multimarker classification of acute lymphoblastic leukemia: evidence for further T subgroups and evaluation of their clinical significance.

Authors: E Thiel; H Rodt; D Huhn; B Netzel; H Grosse-Wilde; K Ganeshaguru; S Thierfelder
Journal: Blood Date: 1980-11 Impact factor: 22.113

4. A monoclonal antibody reactive with human peripheral blood monocytes.

Authors: J Breard; E L Reinherz; P C Kung; G Goldstein; S F Schlossman
Journal: J Immunol Date: 1980-04 Impact factor: 5.422

5. Studies of a human T lymphocyte antigen recognized by a monoclonal antibody.

Authors: E G Engleman; R Warnke; R I Fox; J Dilley; C J Benike; R Levy
Journal: Proc Natl Acad Sci U S A Date: 1981-03 Impact factor: 11.205

6. Ia determinants on human T-cell subsets defined by monoclonal antibody. Activation stimuli required for expression.

Authors: E L Reinherz; P C Kung; J M Pesando; J Ritz; G Goldstein; S F Schlossman
Journal: J Exp Med Date: 1979-12-01 Impact factor: 14.307

7. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody.

Authors: A J McMichael; J R Pilch; G Galfré; D Y Mason; J W Fabre; C Milstein
Journal: Eur J Immunol Date: 1979-03 Impact factor: 5.532

8. A new human T-cell differentiation antigen: unexpected expression on chronic lymphocytic leukemia cells.

Authors: P J Martin; J A Hansen; R C Nowinski; M A Brown
Journal: Immunogenetics Date: 1980 Impact factor: 2.846

9. Tritium radiolabeling of antibodies to high specific activity with N-succinimidyl [2,3-3H] propionate: use in detecting monoclonal antibodies.

Authors: U Kummer; E Thiel; I Doxiadis; M Eulitz; S Sladoljev; S Thierfelder
Journal: J Immunol Methods Date: 1981 Impact factor: 2.303

10. Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.

Authors: M Kamoun; P J Martin; J A Hansen; M A Brown; A W Siadak; R C Nowinski
Journal: J Exp Med Date: 1981-01-01 Impact factor: 14.307

6 in total

1. Quantitation of mu mRNA by in situ hybridization reveals a correlation between B-maturation associated antigens and IgM gene activation in acute lymphatic leukemias.

Authors: K Pachmann; B Dörken; B Emmerich; E Thiel
Journal: Med Oncol Tumor Pharmacother Date: 1988