Literature DB >> 6976820

Behavioral model for diffuse noxious inhibitory controls (DNIC): potentiation by 5-hydroxytryptophan.

E Kraus, J M Besson, D Le Bars.   

Abstract

The effects of the serotonin precursor 5-HTP, were determined in a behavioral DNIC paradigm (increase in vocalization threshold after intraperitoneal injection of the algogenic agent, phenylbenzoquinone). This counter-irritation phenomenon was strongly potentiated by 5-HTP, such potentiation being blocked by the 5-HT receptor blocker, cinanserin. These results are in keeping with those of our recent single unit work in dorsal horn convergent neurons.

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Year:  1982        PMID： 6976820     DOI： 10.1016/0006-8993(82)90384-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  8 in total

1.  Reduction of conditioned pain modulation in humans by naltrexone: an exploratory study of the effects of pain catastrophizing.

Authors:  Christopher D King; Burel Goodin; Lindsay L Kindler; Robert M Caudle; Robert R Edwards; Nikolaus Gravenstein; Joseph L Riley; Roger B Fillingim
Journal:  J Behav Med       Date:  2012-04-26

2.  The effects of 5-HT4 receptor agonist, mosapride citrate, on visceral hypersensitivity in a rat model.

Authors:  Jae Woong Lee; Ki Woon Sung; Oh Young Lee; Seo Eun Lee; Chong Il Sohn
Journal:  Dig Dis Sci       Date:  2012-03-17       Impact factor: 3.199

Review 3.  Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions.

Authors:  Roland Staud
Journal:  Expert Rev Neurother       Date:  2012-05       Impact factor: 4.618

Review 4.  The plasticity of descending controls in pain: translational probing.

Authors:  Kirsty Bannister; A H Dickenson
Journal:  J Physiol       Date:  2017-05-26       Impact factor: 5.182

5.  Sensory signalling effects of tegaserod in patients with irritable bowel syndrome with constipation.

Authors:  J-M Sabaté; D Bouhassira; C Poupardin; A Wagner; Y Loria; B Coffin
Journal:  Neurogastroenterol Motil       Date:  2007-11-14       Impact factor: 3.598

Review 6.  Developments in Understanding Diffuse Noxious Inhibitory Controls: Pharmacological Evidence from Pre-Clinical Research.

Authors:  Mateusz Wojciech Kucharczyk; Diego Valiente; Kirsty Bannister
Journal:  J Pain Res       Date:  2021-04-20       Impact factor: 3.133

7.  Conditioned pain modulation is associated with common polymorphisms in the serotonin transporter gene.

Authors:  Fredrik Lindstedt; Jonathan Berrebi; Erik Greayer; Tina B Lonsdorf; Martin Schalling; Martin Ingvar; Eva Kosek
Journal:  PLoS One       Date:  2011-03-28       Impact factor: 3.240

8.  Involvement of spinal α2 -adrenoceptors in prolonged modulation of hind limb withdrawal reflexes following acute noxious stimulation in the anaesthetized rabbit.

Authors:  John Harris
Journal:  Eur J Neurosci       Date:  2016-02-28       Impact factor: 3.386
  8 in total

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