| Literature DB >> 6975042 |
A Zicca, A Leprini, A Cadoni, A T Franzi, M Ferrarini, C E Grossi.
Abstract
The localization of alpha-naphthyl acid esterase (ANAE) activity in T lymphocytes with receptors for IgM (T(M) cells) have been studied at the electron microscope. The electron-opaque product of the cytochemical reaction was detected around, but never inside, single (or groups of) vesicles, which suggested a possible membrane localization of the enzyme activity. These same vesicles were found to contain acid phosphatase by both light- and electron-microscopic examination and were bound by unit membranes; this data indicates that they likely represent primary lysosomes. The presence of such lysosomes in a restricted paranuclear area is a distinctive feature of T(M) cells.Entities:
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Year: 1981 PMID： 6975042 PMCID： PMC1903855
Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307