| Literature DB >> 6974749 |
J P Capron, J L Lemay, J F Muir, J L Dupas, D Lebrec, J L Gineston.
Abstract
We report a 33-year-old woman who took oral contraceptives for 8 years, and who developed gastrointestinal bleeding from esophageal varices. Celiac and mesenteric angiography demonstrated a portal vein thrombosis. Because of several episodes of dyspnea, a pulmonary angiogram was also performed, and showed partial or complete obstruction of both inferior pulmonary arteries with "pruning" of lower lobes. Despite immediate anticoagulant therapy, the patient died suddenly some days later. We believe that oral contraceptive treatment could have induced thromboembolic disease both in portal and pulmonary circulations in this patient.Entities:
Keywords: Biology; Blood Coagulation Effects; Case Studies; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods--side effects; Diarrhea; Diseases; Embolism; Endocrine System; Estrogens; Family Planning; Gastrointestinal Effects; Hematological Effects; Hemic System; Hormones; Norgestrel; Oral Contraceptives--side effects; Physiology; Research Methodology; Studies; Thromboembolism; Thrombosis; Vascular Diseases
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Year: 1981 PMID： 6974749 DOI： 10.1097/00004836-198109000-00016
Source DB: PubMed Journal: J Clin Gastroenterol ISSN： 0192-0790 Impact factor: 3.062